DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dbp80 and ddx25

DIOPT Version :9

Sequence 1:	NP_001263168.1	Gene:	Dbp80 / 3354919	FlyBaseID:	FBgn0024804	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001016345.1	Gene:	ddx25 / 549099	XenbaseID:	XB-GENE-958136	Length:	479	Species:	Xenopus tropicalis

Alignment Length:	421	Identity:	238/421 - (56%)
Similarity:	311/421 - (73%)	Gaps:	6/421 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EETDFDVADPAETSLLIKILGKGLVNTKLSLDIQQKNPNSPLHSVKTFEALHLKASLLKGIYAMG 92
            ||:|.|  |||..|||.|:|.:.|:::..|:::.|::|.|||.|||:||.||||..||:||||||
Frog    50 EESDID--DPANQSLLNKLLRRTLIDSSHSVEVSQRDPTSPLFSVKSFEKLHLKDELLRGIYAMG 112

  Fly    93 FNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAI 157
            ||.||||||.|||.:|||||||:||||||||||||||||||||||:....:||.:|||||:|||:
Frog   113 FNRPSKIQENALPMMLADPPQNLIAQSQSGTGKTAAFVLAMLSRVDAKKTYPQCMCLSPTFELAL 177

  Fly   158 QTGEVAARMGQFCREIKLRFAVRGEEVDRSKKIEEHILIGTPGKLLDWGIKFRLFDMKKISVFVL 222
            |||:|...||:||..||:.:||||....:..:||..|:|||||.:|||..|.||.::|.||||||
Frog   178 QTGKVVEEMGKFCNGIKVIYAVRGNRPGKGTQIEAQIVIGTPGTVLDWCFKLRLINVKNISVFVL 242

  Fly   223 DEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLEN 287
            |||||||..|||.|..:|:.:.:...||||.||||:|..|..||..||.||.||:|.:||.:|:|
Frog   243 DEADVMINVQGHSDHSVRVKRSMPKTCQMLLFSATFGDSVWAFAERIVPDPNIIKLKKEELTLDN 307

  Fly   288 IKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQ 352
            |:|:|.||:|:|.||:|:.|:||.|::.|||:||.|::.|.||:..|..|||.||:|:|:|:|..
Frog   308 IQQFYDKCENKEQKYSALCNMYGIITIAQAIVFCQTRKIANWLSRHMLEDGHQVALLSGELSVCD 372

  Fly   353 RLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPS 417
            |.:::.|||.|.:|||:|||:.:||||:|||:|||||||||::||..|.|||||||||||||...
Frog   373 RAEMIQRFREGKDKVLVTTNVCARGIDVEQVSIVVNFDLPVNVDGSVDFETYLHRIGRTGRFGKK 437

  Fly   418 A----LTRNSPIFGVKAESGKIGKEINRSSS 444
            .    |..||.::.:|........:|.:.:|
Frog   438 GIAVNLIENSFVYMLKEIEEHFNTKIKKLNS 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc	75..277	CDD:238167	128/201 (64%)
		DEXDc	88..291	CDD:214692	126/202 (62%)
		Helicase_C	299..414	CDD:278689	68/114 (60%)
ddx25	NP_001016345.1	PTZ00424	92..466	CDD:185609	217/373 (58%)
		P-loop_NTPase	95..297	CDD:304359	128/201 (64%)
		HELICc	307..443	CDD:238034	77/135 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I2811
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	506	1.000	Inparanoid score	I1305
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D254883at33208
OrthoFinder	1	1.000	-	-		FOG0001995
OrthoInspector	1	1.000	-	-		oto104215
Panther	1	1.100	-	-	O	PTHR47958
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160