Protein Alignment Dbp80 and Eif4a3l2

DIOPT Version :10

• Sequence 1: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_001423114.1
• Gene: Eif4a3l2 / 434080
• MGIID: 3646594
• Length: 411
• Species: Mus musculus
• Alignment Length: 384
• Identity: 133/384 - (34%)
• Similarity: 227/384 - (59%)
• Gaps: 21/384 - (5%)

  Fly    74 TFEALHLKASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVN 138
            ||:.:.|:..||:||||.||..||.||:.|:..::..  :::||||||||||||.|.:::|..::
Mouse    39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISVLQCLD 101

  Fly   139 VCLNHPQVLCLSPTYELAIQTGEVAARMGQFCREIKLRFAVRGEEVDRS-KKIE--EHILIGTPG 200
            :.:...|.|.|:||.|||:|..:....:|.: ..::....:.|..|... :|::  :|::.||||
Mouse   102 IQVRETQALILAPTRELAVQIQKGLLALGDY-MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPG 165

  Fly   201 KLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMDF 265
            ::.|. |:.|....:.|.:.||||||.|: .:|..:|...:::.|.|..|::..|||...|:::.
Mouse   166 RVFDM-IRRRSLPTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEM 228

  Fly   266 ARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWL 330
            ....:..|..|.:.|:|.:||.|||::|..:.||.|::.:.::|..:::.||:|||.|||...||
Mouse   229 TNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWL 293

  Fly   331 AAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDL 395
            ..||.....:|:.:.||:...:|..::..||||..:|||:|::.:||:|:.||::::|:|||
Mouse   294 TEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLP--- 355

  Fly   396 DGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGKIGKEINRSSSGAESGSREMP 454
               .:.|.|:|||||:||:....:..|.    ||.:..:|.::|.:..|   :...|||
Mouse   356 ---NNRELYIHRIGRSGRYGRKGVAINF----VKNDDIRILRDIEQYYS---TQIDEMP 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	67/199 (34%)
		SF2_C_DEAD	288..414	CDD:350174	49/125 (39%)
Eif4a3l2	NP_001423114.1	DEAD-like_helicase_N	22..411	CDD:475120	133/384 (35%)