DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dbp80 and CG9630

DIOPT Version :9

Sequence 1:	NP_001263168.1	Gene:	Dbp80 / 3354919	FlyBaseID:	FBgn0024804	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	109/434 - (25%)
Similarity:	192/434 - (44%)	Gaps:	98/434 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LKASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHP 144
            |..::|:.:.:.||...:.:|..|:|.|||  .:::.|::.:|:|||.||::.||..:.  ..|.
  Fly    14 LSDAVLQVVQSFGFQQMTPVQTAAIPLLLA--RKDVSAEAVTGSGKTLAFLVPMLEILQ--RRHK 74

  Fly   145 Q---------VLCLSPTYELAIQTGEVAARMGQF-----CREIKLRFAVRG----EEVDRSKKIE 191
            :         .|.:|||.|||.|..||.|   ||     ...:..:..|.|    |::...::..
  Fly    75 ETPWGPKEIGALVISPTRELARQISEVLA---QFLEHEDLEHLNQQLIVGGNSIEEDIATLRRET 136

  Fly   192 EHILIGTPGKLLDWGIKFRLF-----------DMKKISVFVLDEADVMIATQGHHDQCIRIHKML 245
            ..||:.|||:|.|      ||           .:|.:...||||||.:: ..|.......|...|
  Fly   137 PCILVCTPGRLED------LFQRKGDDLNLAAQVKSLEFLVLDEADRLL-DLGFKTSVNNILGYL 194

  Fly   246 NPHCQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLE---NIKQYYVKCKNEEGKYNAIQN 307
            ....:...||||...||.|..|..:.:|.::. ::|:.|:.   .::.:| :....|.|:.|:..
  Fly   195 PRQRRTGLFSATQTTEVTDLIRAGLRNPVLVS-VKEKASVNTPARLQNFY-RIVEPELKFVALLE 257

  Fly   308 IYG--CISVGQAIIFCHT----------------KRTAAWLAAKMTSDGHSVAVLTGDLTVVQRL 354
            ...  ...:|:.::|..|                |||...:..||.:               :|.
  Fly   258 FLSSPATVIGKVMVFFPTCACVEYWAEALPPLLPKRTVLGIHGKMKN---------------KRA 307

  Fly   355 DVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPSAL 419
            :|:::||:..:.||:.|::|:||:|:.::..||.:|.|      :...:::||:|||.|   ...
  Fly   308 NVVEKFRNTPQAVLLCTDVLARGLDVPEIEWVVQWDPP------STASSFVHRVGRTAR---QGN 363

  Fly   420 TRNSPIFGVKAESG-----KIGKEINRS---SSGAESGSREMPK 455
            ..|:.:|.:.:|..     ||.:::..:   :..||...||..|
  Fly   364 EGNALVFLLPSEDAYVHFLKINQKVELTKLLTEEAEDADREKKK 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc	75..277	CDD:238167	64/225 (28%)
		DEXDc	88..291	CDD:214692	64/234 (27%)
		Helicase_C	299..414	CDD:278689	31/132 (23%)
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	64/225 (28%)
		DEXDc	22..232	CDD:214692	63/224 (28%)
		HELICc	239..370	CDD:238034	34/155 (22%)
		DUF4217	411..470	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930