Protein Alignment Dbp80 and eif4a2

DIOPT Version :10

• Sequence 1: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_998616.2
• Gene: eif4a2 / 406760
• ZFINID: ZDB-GENE-040426-2802
• Length: 411
• Species: Danio rerio
• Alignment Length: 370
• Identity: 138/370 - (37%)
• Similarity: 220/370 - (59%)
• Gaps: 21/370 - (5%)

  Fly    75 FEALHLKASLLKGIYAMGFNTPSKIQETA-LPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVN 138
            |:.::||.:||:||||.||..||.||:.| :|.:..   .::|||:||||||||.|.:::|.::.
Zfish    39 FDDMNLKETLLRGIYAYGFEKPSAIQQRAIIPCIKG---YDVIAQAQSGTGKTATFAISILQQLE 100

  Fly   139 VCLNHPQVLCLSPTYELAIQTGEVAARMGQF----CREIKLRFAVRGEEVDRSKKIEEHILIGTP 199
            :.....|.|.|:||.|||.|..:|...:|.:    |........|| .|:.:.:....||::|||
Zfish   101 IEQKETQALVLAPTRELAQQIQKVILALGDYMGASCHACIGGTNVR-NEMQKLQAEAPHIVVGTP 164

  Fly   200 GKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMD 264
            |::.|. :..|....|.|.:|||||||.|: ::|..||...|.:.|:.:.|::..|||...:|::
Zfish   165 GRVFDM-LNRRYLSPKWIKMFVLDEADEML-SRGFKDQIYEIFQKLSTNIQVVLLSATMPADVLE 227

  Fly   265 FARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAW 329
            .....:.:|..|.:.:||.:||.|||:|:..:.||.|.:.:.::|..:::.||:||.:|:|...|
Zfish   228 VTTKFMREPVRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDW 292

  Fly   330 LAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVD 394
            |..||.:...:|:.|.||:...:|..::..||||..:|||||::|:||||::||::|:|:|||.:
Zfish   293 LTEKMHARDFTVSALHGDMDQKERDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTN 357

  Fly   395 LDGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGKIGKEI 439
            .      |.|:|||||.|||....:..|.    |..|..:|.::|
Zfish   358 R------ENYIHRIGRGGRFGRKGVAINF----VTEEDKRILRDI 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	73/201 (36%)
		SF2_C_DEAD	288..414	CDD:350174	52/125 (42%)
eif4a2	NP_998616.2	DEAD-like_helicase_N	25..411	CDD:475120	138/370 (37%)