Protein Alignment Dbp80 and eif4a1a

DIOPT Version :10

• Sequence 1: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_938180.1
• Gene: eif4a1a / 386634
• ZFINID: ZDB-GENE-031030-2
• Length: 406
• Species: Danio rerio
• Alignment Length: 348
• Identity: 135/348 - (38%)
• Similarity: 213/348 - (61%)
• Gaps: 17/348 - (4%)

  Fly    72 VKTFEALHLKASLLKGIYAMGFNTPSKIQETA-LPTLLADPPQNMIAQSQSGTGKTAAFVLAMLS 135
            |.:|:.::|:.:||:||||.||..||.||:.| ||.:..   .::|||:||||||||.|.:::|.
Zfish    31 VDSFDDMNLREALLRGIYAYGFEKPSAIQQRAILPCIKG---YDVIAQAQSGTGKTATFAISILQ 92

  Fly   136 RVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQF----CREIKLRFAVRGEEVDRSKKIEEHILI 196
            :::|.|...|.:.|:||.|||.|..:|...:|.:    |........|| .:|.:.:....||::
Zfish    93 QIDVELKATQAMVLAPTRELAQQIQKVVLALGDYMGATCHACIGGTNVR-NDVQKLQADVPHIVV 156

  Fly   197 GTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKE 261
            ||||::.|. :..|....|.|.:|.|||||.|: ::|..||...|.:.|....|::..|||..:|
Zfish   157 GTPGRVFDM-LNRRYLSPKYIKMFALDEADEML-SRGFKDQIYEIFQKLATDTQVILLSATMPQE 219

  Fly   262 VMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRT 326
            |::.....:.||..|.:.:||.:||.|:|:|:..:.||.|.:.:.::|..:::.||:||.:|:|.
Zfish   220 VLEVTTKFMRDPVRILVKKEELTLEGIRQFYINVEKEEWKLDTLCDLYETLTITQAVIFINTRRK 284

  Fly   327 AAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDL 391
            ..||..||.:...:|:.|.||:...:|..::..||||..:|||||::|:||||::||::|:|:||
Zfish   285 VDWLTEKMHARDFTVSALHGDMEQKERDVIMKEFRSGSSRVLITTDLLARGIDVQQVSLVINYDL 349

  Fly   392 PVDLDGMADCETYLHRIGRTGRF 414
            |.:.      |.|:|||||.|||
Zfish   350 PTNR------ENYIHRIGRGGRF 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	75/201 (37%)
		SF2_C_DEAD	288..414	CDD:350174	51/125 (41%)
eif4a1a	NP_938180.1	DEAD-like_helicase_N	20..406	CDD:475120	135/348 (39%)