Protein Alignment Dbp80 and Eif4a2

DIOPT Version :10

• Sequence 1: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_001334108.1
• Gene: Eif4a2 / 13682
• MGIID: 106906
• Length: 408
• Species: Mus musculus
• Alignment Length: 386
• Identity: 144/386 - (37%)
• Similarity: 226/386 - (58%)
• Gaps: 26/386 - (6%)

  Fly    64 NPNSPLHS-----VKTFEALHLKASLLKGIYAMGFNTPSKIQETA-LPTLLADPPQNMIAQSQSG 122
            :|:..:.|     |..|:.::||.|||:||||.||..||.||:.| :|.:..   .::|||:|||
Mouse    20 DPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKG---YDVIAQAQSG 81

  Fly   123 TGKTAAFVLAMLSRVNVCLNHPQVLCLSPTYELAIQTGEVAARMGQF----CREIKLRFAVRGEE 183
            |||||.|.:::|.::.:.....|.|.|:||.|||.|..:|...:|.:    |........|| .|
Mouse    82 TGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVR-NE 145

  Fly   184 VDRSKKIEEHILIGTPGKLLDWGIKFRLFDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPH 248
            :.:.:....||::||||::.|. :..|....|.|.:|||||||.|: ::|..||...|.:.||..
Mouse   146 MQKLQAEAPHIVVGTPGRVFDM-LNRRYLSPKWIKMFVLDEADEML-SRGFKDQIYEIFQKLNTS 208

  Fly   249 CQMLFFSATYGKEVMDFARLIVADPTIIRLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCIS 313
            .|::..|||...:|::..:..:.||..|.:.:||.:||.|||:|:..:.||.|.:.:.::|..::
Mouse   209 IQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLT 273

  Fly   314 VGQAIIFCHTKRTAAWLAAKMTSDGHSVAVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGI 378
            :.||:||.:|:|...||..||.:...:|:.|.||:...:|..::..||||..:|||||::|:|||
Mouse   274 ITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGI 338

  Fly   379 DIEQVTIVVNFDLPVDLDGMADCETYLHRIGRTGRFEPSALTRNSPIFGVKAESGKIGKEI 439
            |::||::|:|:|||.:.      |.|:|||||.|||....:..|.    |..|..:|.::|
Mouse   339 DVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINF----VTEEDKRILRDI 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	76/201 (38%)
		SF2_C_DEAD	288..414	CDD:350174	52/125 (42%)
Eif4a2	NP_001334108.1	DEAD-like_helicase_N	9..408	CDD:475120	144/386 (37%)
		Q motif	34..62		15/27 (56%)
		DEAD box	184..187		2/2 (100%)