Protein Alignment Dbp80 and DDX19B

DIOPT Version :10

• Sequence 1: NP_001263168.1
• Gene: Dbp80 / 3354919
• FlyBaseID: FBgn0024804
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_001350867.1
• Gene: DDX19B / 11269
• HGNCID: 2742
• Length: 484
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 239/406 - (58%)
• Similarity: 312/406 - (76%)
• Gaps: 2/406 - (0%)

  Fly    17 VDKLNLDSKSGEETDFDVADPAETSLLIKILGKGLVNTKLSLDIQQKNPNSPLHSVKTFEALHLK 81
            |.|.|.:::..:|.:.:  |.|..|||.|::...||:....:::.|::|||||:|||:||.|.||
Human    43 VVKTNANAEKTDEEEKE--DRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLK 105

  Fly    82 ASLLKGIYAMGFNTPSKIQETALPTLLADPPQNMIAQSQSGTGKTAAFVLAMLSRVNVCLNHPQV 146
            ..||:|:||||||.||||||.|||.:||:||||:||||||||||||||||||||:|.....:||.
Human   106 PQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQC 170

  Fly   147 LCLSPTYELAIQTGEVAARMGQFCREIKLRFAVRGEEVDRSKKIEEHILIGTPGKLLDWGIKFRL 211
            ||||||||||:|||:|..:||:|..|:||.:||||.:::|.:||.|.|:|||||.:|||..|.:.
Human   171 LCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQIVIGTPGTVLDWCSKLKF 235

  Fly   212 FDMKKISVFVLDEADVMIATQGHHDQCIRIHKMLNPHCQMLFFSATYGKEVMDFARLIVADPTII 276
            .|.|||.||||||||||||||||.||.|||.:||..:||||.||||:...|..||:.:|.||.:|
Human   236 IDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVI 300

  Fly   277 RLMREEESLENIKQYYVKCKNEEGKYNAIQNIYGCISVGQAIIFCHTKRTAAWLAAKMTSDGHSV 341
            :|.||||:|:.||||||.|.:.:.|:.|:.|:||.|::.||:|||||::||:||||:::.:||.|
Human   301 KLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQV 365

  Fly   342 AVLTGDLTVVQRLDVLDRFRSGLEKVLITTNILSRGIDIEQVTIVVNFDLPVDLDGMADCETYLH 406
            |:|:|::.|.||..|::|||.|.||||:|||:.:||||:|||::|:|||||||.||..|.|||||
Human   366 ALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLH 430

  Fly   407 RIGRTGRFEPSALTRN 422
            ||||||||....|..|
Human   431 RIGRTGRFGKRGLAVN 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp80	NP_001263168.1	DEADc_DDX19_DDX25	80..277	CDD:350721	128/196 (65%)
		SF2_C_DEAD	288..414	CDD:350174	76/125 (61%)
DDX19B	NP_001350867.1	DEAD-like_helicase_N	80..308	CDD:475120	145/227 (64%)
		SF2_C_DEAD	312..448	CDD:350174	80/135 (59%)