Protein Alignment vtd and Rad21l

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001263329.1
• Gene: Rad21l / 668929
• MGIID: 3652039
• Length: 552
• Species: Mus musculus
• Alignment Length: 733
• Identity: 246/733 - (33%)
• Similarity: 347/733 - (47%)
• Gaps: 207/733 - (28%)

  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVR 65
            |||.|::::|:||||:|||||||:||:|||||||.|:|.:::.|:.||||:||||||||||||||
Mouse     1 MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKIISPKVKIALRTSGHLLLGVVR 65

  Fly    66 IYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDFDTALPELNDIDIE 130
            ||:||||||||||:|||:|:||.||||:||||:.:.||..|.|||||.||||:  :..:|:|||.
Mouse    66 IYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFE--IYNINEIDIS 128

  Fly   131 AQFSINQSRADEITMREDYGSLSLSLQDDGFGDIGFEAETPEIIRCSIPSNINDKIFDNDVLENI 195
            ...:.||||.:|||:||:| |..|..|...|||      .|||:|       ....||:::|.|.
Mouse   129 EPLAQNQSRPEEITLREEY-SNDLLFQAGSFGD------EPEILR-------RHSFFDDNILMNS 179

  Fly   196 ESL-DPHSLDAHADMPGSRLD-GDGFGDSFGQPALFEDDLFGDPSQPVEQ--ITKE--------S 248
            ..| ..||..:.|:......| ||||||. |......|:|..|.|..:|:  :.||        |
Mouse   180 SGLVVEHSSGSFAEEKSLFFDNGDGFGDE-GAAGEMIDNLLQDESTFLEEAYLNKEVSLPPELPS 243

  Fly   249 TTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHASVSENVPMNEITLVQNEDEGF 313
            :.::...:||:..|.                |||:                :|||||:.||||||
Mouse   244 SIMVEPGNSDDQCIP----------------EDEE----------------INEITLLSNEDEGF 276

  Fly   314 ALAPLDVSMYKGVTKAKRKRKLIIDEIKNISGEEMKAQLADTSDILTTLDLAPPTKRLMYWKETG 378
            .|.|:| .:.....:.::||:|::|.:|.||.:.|..|||...|.|..|||||||:|||.||:.|
Mouse   277 TLDPID-DLDIADRRRRKKRRLLVDPVKEISSKAMHRQLASFMDTLMVLDLAPPTQRLMMWKKRG 340

  Fly   379 GVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVPMEILALEFYTKENENALIIFNKKG 443
            ||:.|.|..::.     |..:..:.||:..                  |.:.:.:.|.:...:..
Mouse   341 GVDMLLSTATQD-----LINDELKMLFTKC------------------FLSSDYKLAKLTLKESV 382

  Fly   444 RKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRA--NHKSLGV----STVSVEIVSKEQESISCQNE 502
            ||...:               |.:..|.|:..  :|..|..    ..|:.|.|...||:::.
Mouse   383 RKEVGN---------------QQIAEPSVMGEPNSHSELDQPQDWKDVTDESVGSFQENVNM--- 429

  Fly   503 LTFFDNMRS-PDLLSL--NEMEQFSSINELPLTPRNMNHEMGDDFNQGDSTPAGLDHGHATPQHG 564
                 |:.| .|:|.:  ..:|..||          ||..:..     ::.||.|
Mouse   430 -----NVNSEQDILGMISPAVEGLSS----------MNGSLAQ-----ENCPAEL---------- 464

  Fly   565 NIGEMDHDSVIPTKKTAVILNESVGTSVLSDNGVSKRTNNILKGWDNYEIPSFVGQNHGDEQMEN 629
                                 ||.|:.                                    :|
Mouse   465 ---------------------ESSGSK------------------------------------QN 472

  Fly   630 ETDEQFEERVLNKRAAHLFIDVRAHF--IAKDSLELSQLTSGNSRKQAAQKFYSLLVLKKFKVLH 692
            ...|::.:|:...      ::|...|  :...|..|.:|...:.|||||.|||:||:|||.:.:.
Mouse   473 TEAEKWNQRLFQT------LNVLREFNKMGMQSFSLKKLCRNSDRKQAAAKFYTLLILKKHRAIE 531

  Fly   693 IDQSAPYADITITRGPTF 710
            :.||.|||||..|.||.|
Mouse   532 LSQSVPYADIIATVGPMF 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	72/101 (71%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	31/76 (41%)
		Rad21_Rec8	657..710	CDD:335912	26/52 (50%)
Rad21l	NP_001263329.1	Rad21_Rec8_N	1..104	CDD:461446	73/102 (72%)
		Rad21_Rec8_M_NXP1-like	297..369	CDD:439294	32/94 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		5/19 (26%)
		Rad21_Rec8	498..549	CDD:335912	26/50 (52%)