Protein Alignment vtd and Rad21

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001020872.1
• Gene: Rad21 / 314949
• RGDID: 1594529
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 758
• Identity: 292/758 - (38%)
• Similarity: 392/758 - (51%)
• Gaps: 174/758 - (22%)

  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVR 65
            |||.|.:|:|:||||:||||||||||:|||||||.|:|.|||.|:.||||:||||||||||||||
  Rat     1 MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVR 65

  Fly    66 IYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDFDTALPELNDIDIE 130
            ||.||||||||||||||:|||||||||:|||||.:|||..|||||||.|||||..||:|:|||:.
  Rat    66 IYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVA 130

  Fly   131 AQFSINQSRADEITMREDYGSLSLSLQDDGFGDIGFEAETPEIIR-------------------- 175
            .|||:||||.:||||||:.|::|: ||::.|||.|.:..  ||:|
  Rat   131 QQFSLNQSRVEEITMREEVGNISI-LQENDFGDFGMDDR--EIMREGSAFEDDDMLVSTSASNLL 192

  Fly   176 ---CSIPSNINDKIFDNDVLENIESLDPHSLDAHA---------DMPGSRLDGDGFGDSFGQPAL 228
               ....||:|:||      .::|..|.:..|...         |...|..||..|.|   .|||
  Rat   193 LEPEQSTSNLNEKI------NHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGGIFDD---PPAL 248

  Fly   229 FEDDLFGDPSQPVEQITKESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHAS 293
            .|..:. .|.||..            ||.|||...::....||.:  |:.:|
  Rat   249 SETGVM-LPEQPAH------------DDMDEDDNGSLGGPDSPDS--VDPVE------------- 285

  Fly   294 VSENVPM----NEITLVQNEDEGFALAPLDVSMYKGVTKAKRKRKLIIDEIKNISGEEMKAQLAD 354
                 ||    ::.|||.||:|.|||.|:|:::.:  ||||||||||:|.:|.:..:.::|||:|
  Rat   286 -----PMPTMTDQTTLVPNEEEAFALEPIDITVKE--TKAKRKRKLIVDSVKELDSKTIRAQLSD 343

  Fly   355 TSDILTTLDLAPPTKRLMYWKETGGVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVP 419
            .|||:||||||||||:||.|||||||||||||     ||:.|:.|...:||:..     .:.:||
  Rat   344 YSDIVTTLDLAPPTKKLMMWKETGGVEKLFSL-----PAQPLWNNRLLKLFTRC-----LTPLVP 398

  Fly   420 MEILALEFYTKENENALIIFNKKGRKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRANHKSLGVST 484
            .::                    .::||.....||      |..::..|.|||.|
  Rat   399 EDL--------------------RKRRKGGEADNL------DEFLKEFENPEVPR---------- 427

  Fly   485 VSVEIVSKEQESISCQNELTFFDNMRSPDLLSLNEME-QFSSINEL---PLTPRNMNHEMGDDFN 545
               |....:.:....|.::.....:..|..|..:.|| ..::|.|.   |..|:.:..:.|
  Rat   428 ---EEQQPQPQQQQAQRDVIDEPIIEEPSRLQDSVMEASRTNIEESAMPPPPPQGVKRKAG---- 485

  Fly   546 QGDSTPAGLDHGHATPQHGNIGEMDHDSV-IPTKKTAVILNESVGTSVLSDNGVSKRTNNILKGW 609
            |.|..||      ..||  .:.:|:...| :|.::...|........:|.:....|..
  Rat   486 QVDPEPA------IPPQ--QVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEK------- 535

  Fly   610 DNYEIPSFVGQNHGDEQMENET----DEQFEERVLNKRAAHLFIDVRAHFIAK---DSLELSQLT 667
                      :...:|:.|:|.    |:..|||..|||...:...:: ..:||   :|:.|.:|.
  Rat   536 ----------EKEEEEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQ-RALAKTGAESISLLELC 589

  Fly   668 SGNSRKQAAQKFYSLLVLKKFKVLHIDQSAPYADITITRGPTF 710
            ...:|||||.||||.|||||.:.:.:.|..||:||..|.||.|
  Rat   590 RNTNRKQAAAKFYSFLVLKKQQAIELTQEEPYSDIIATPGPRF 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	82/101 (81%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	48/76 (63%)
		Rad21_Rec8	657..710	CDD:335912	27/55 (49%)
Rad21	NP_001020872.1	Rad21_Rec8_N	1..104	CDD:461446	83/102 (81%)
		Rad21_Rec8_M_NXP1-like	316..395	CDD:439294	50/88 (57%)
		Rad21_Rec8	578..632	CDD:335912	25/53 (47%)