Protein Alignment vtd and Rec8

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001011916.1
• Gene: Rec8 / 290227
• RGDID: 1309376
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 776
• Identity: 156/776 - (20%)
• Similarity: 254/776 - (32%)
• Gaps: 253/776 - (32%)

  Fly     2 FYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQ-------------PKVKLAL 53
            :|.:::....|..|.|||||....::.|....:.|:.|:.|.||.             |:.:.:|
  Rat     3 YYPNVLQRHTGCFATIWLAATRGSRLVKREYLKVNVVKTCEEILNYVLVRVQPPMPGLPRPRFSL 67

  Fly    54 RTSGHLLLGVVRIYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLP------E 112
            ..|..|.:||:|:|.::.:||:.|.......:..|.....:|:    .||::.::.||      |
  Rat    68 YLSAQLQIGVIRVYFQQCQYLVEDIQHILEHLHRAQLRIRIDM----EEADLPSLLLPNCLAMME 128

  Fly   113 VFHD----------FDTALPELNDID-----IEAQF--SINQSRADEITMREDYGSLSLSLQDDG 160
            ...|          .|..||...||.     :||..  .|.:....|.|........:|::
  Rat   129 TLEDAPEPFFGTMSVDPTLPSPFDIPQIRHLLEAATPEKIREETLPEATPEPRKPDRTLAM---- 189

  Fly   161 FGDIGFEAETPEIIRCSIPSNINDKIFDNDVLENIESLDPHSLDAHADMPG-SRLDGDGFGDSFG 224
                   .::||:|                .|:..|.:....::...|:|. ||.|.|.......
  Rat   190 -------VQSPEVI----------------TLQEAEPIRMLRIEGEQDLPEISRGDLDLLIAEED 231

  Fly   225 QPALFEDDLFG------DPSQPVEQITKESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIED-- 281
            ...|.|:...|      ..|.|::: :||....|..|..       :.::..||.:.|..|.:
  Rat   232 DAILLEERQRGRLLRQRRASPPLDE-SKEEPRALEGDGL-------VSSLSPPAPAQVEGIREPL 288

  Fly   282 -----EKEENNLNG---HASVSENVPMNEITLVQNEDEGFALAPLDV-----SMYKGVTKAKRKR 333
                 ..|...:.|   ...::|..|..|:.|.         ||..:     |..:...:.:|.|
  Rat   289 PDQAFPPEVQKMPGWEPGVLLTEVTPPQELRLP---------APPSIEKRPPSPQRPPRRRRRGR 344

  Fly   334 KLII-DEIKNISGEEMKAQLADTSDILTTLDLAPPTKRLMYWKETGGVEKLFSLPSRSIPARALF 397
            :|:. |:...||.|:.:.||...:.......:.||.::||      ...:||..|:       |.
  Rat   345 QLLFWDKETQISREKFEEQLQTGAHCCEYPVVQPPKRKLM------SPAELFRTPT-------LS 396

  Fly   398 GNYNRQLFSHSTFFEDFSSVVPMEILAL--EFYTKENENALIIFNKKGRKRKNDNMSNLFLDHVP 460
            |..:.:|.:..|    ..:.||..:|..  :..|:|......:.:|:.| ||.:.:|.:
  Rat   397 GWLSPELLALWT----HCAQVPPRMLRQRPQLETEETVEEERVADKEER-RKTEALSEI------ 450

  Fly   461 DSVVQSLEAPEVLRANHKSLG----VSTVSVEIVSKEQESISC--QNELTFFDNMRSPDLLSLNE 519
                      ||||...:..|    .|.:|:|:..:|:...|.  ..|...:...|.|      |
  Rat   451 ----------EVLREAQEPSGPLMLSSELSLEVAEEEKSRTSFIPPEERWAWIEERQP------E 499

  Fly   520 MEQFSSINELPLTPRNMNHEMGDDFNQGDSTPAGLDHGHATPQHGNIGEMDHDSVIPTKKTAVIL 584
            ......:.|||..|..|
  Rat   500 PPALPMLPELPEVPMEM------------------------------------------------ 516

  Fly   585 NESVGTSVLSDNGVSKRTNNILKGWDNYEIPSFVGQNHGDEQMENETDEQFEERVLNKRAAHLFI 649
              ..|..:||                                         .|.||...|..|..
  Rat   517 --PPGPELLS-----------------------------------------SEAVLRAVALELQA 538

  Fly   650 DVRAHFIAKDSLELSQLTSGNSRKQAAQKFYSLLVLKKFKVLHIDQSAPYADITITRGPTF 710
            :....|       .|.:...:|||.|::.||.||||...|:|.:||..||..:.|..||.|
  Rat   539 NREPDF-------SSLVPPLSSRKLASRVFYLLLVLSAQKILLVDQQKPYGRLLIRLGPKF 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	27/113 (24%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	18/77 (23%)
		Rad21_Rec8	657..710	CDD:335912	20/52 (38%)
Rec8	NP_001011916.1	Rad21_Rec8_N	1..112	CDD:461446	27/112 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	247..282		8/42 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	317..344		6/35 (17%)
		Rad21_Rec8_M_Rec8	347..414	CDD:439296	17/83 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..444		5/22 (23%)
		Rad21_Rec8	538..592	CDD:335912	21/60 (35%)