Protein Alignment vtd and rec8

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_596059.1
• Gene: rec8 / 2540458
• PomBaseID: SPBC29A10.14
• Length: 561
• Species: Schizosaccharomyces pombe
• Alignment Length: 645
• Identity: 127/645 - (19%)
• Similarity: 228/645 - (35%)
• Gaps: 214/645 - (33%)

  Fly     1 MFYEHIILAK-KGPLARIWLAA-----HWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHL 59
            |||...:|.| ||.:..|||||     |..:|:.|..:...:|:::.:.:......||||.|.:|
pombe     1 MFYNQDVLTKEKGGMGVIWLAATLGSKHSLRKLHKKDIMSVDIDEACDFVAFSPEPLALRLSSNL 65

  Fly    60 LLGVVRIYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDFDTALPEL 124
            ::||.|:::.:..:..:..:...::::...                          |..|:.| .
pombe    66 MIGVTRVWAHQYSFFHSQVSTLHLRVRKEL--------------------------DHFTSKP-F 103

  Fly   125 NDIDIEAQFSINQSRADEITMRED---------YGSLSLSLQDDGFGDIGF--EAETPEIIRCSI 178
            .:|||:.:    |:...::.:.||         |.:.:|...|.......|  ..|.|.|
pombe   104 KNIDIQNE----QTNPKQLLLAEDPAFIPEVSLYDAFNLPSVDLHVDMSSFTQPKENPNI----- 159

  Fly   179 PSNINDKIFDNDVLENIESLDPHSLDAHADMP-----GSRLDGDGFGDSFGQPALFEDDLFGDPS 238
                       .|||.:.....:.::...:..     .|.:..|....|..:|..||.|..||
pombe   160 -----------SVLETLPDSTSYLINTSQNYSLRNNVSSFVYEDSRAFSTEEPLDFEFDENGD-- 211

  Fly   239 QPVEQITKESTTVLNADDS-------------------------------DEDAIDNIHNVPSPA 272
              ::::||.:   :|:|.|                               |||.:.    :|.|.
pombe   212 --IQELTKGT---INSDPSLQAASQHSNLGSVQREYNSEEQESRIHMFEIDEDVLP----LPVPL 267

  Fly   273 TSLVNSIEDEKEENNLNGH-----ASVSENVPMNEITLVQ---NEDEGFALAPLDVSMY---KGV 326
            .|:::|..:|.|...|...     ....||:.::..||.|   |..|  .:..|:.:.|   :|.
pombe   268 QSVMDSEHNENEPRALKRRKVQKLLEPDENIELSTRTLSQWRKNYVE--RMIALEATKYVRRRGA 330

  Fly   327 TKAKRKR--------------KLIIDEIK--NISGEEMKAQL--ADTSDILTTLDLAPPTKRLMY 373
            :.||:|.              |..|:::|  |.:..|:...|  .|||::....|:.......:.
pombe   331 SSAKKKELNKFFDWESFHPLLKPWIEKLKPSNNTPSEIDDVLRNIDTSEVEVGRDVQGELGLNIP 395

  Fly   374 W---------------KETGGVEKLFSLP------------SRSIPARALFGNYNRQLFSHSTFF 411
            |               .:||...   |.|            |.|:|:|..|    ......|.|.
pombe   396 WNTSSRSNSAINSKSHSQTGSEH---STPLLDTKYRKRLPHSPSMPSRVEF----LPALESSQFH 453

  Fly   412 EDFSSVVPMEILALEFYTKEN---ENALI------------------IFNKKGRKRKNDNMSNLF 455
            |..:|.:.:: |:.:|...:|   |||.:                  |:...||...:..:.|
pombe   454 ETLNSELSLQ-LSDDFVLYKNTQEENAHLMLSMEKECANFYEYAKTAIYENNGRITFSSLLPN-- 515

  Fly   456 LDHVPDSVVQSLEAPEVLRANHKSLGVSTVSVEIVSKEQESISCQNELTFFDNMRSPDLL 515
                      .|:.|.|.:|....|.::|.|..:|.:::.    .:|::...|::|.|.:
pombe   516 ----------DLKRPVVAQAFSHLLSLATKSAFLVKQDKP----YSEISVSLNLKSTDAI 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	25/107 (23%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	23/121 (19%)
		Rad21_Rec8	657..710	CDD:335912
rec8	NP_596059.1	Rad21_Rec8_N	1..95	CDD:461446	25/93 (27%)
		Rad21_Rec8_M_SpRec8p-like	284..386	CDD:439291	22/103 (21%)
		Rad21_Rec8	503..557	CDD:335912	13/69 (19%)