Protein Alignment vtd and rad21

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_588151.1
• Gene: rad21 / 2539447
• PomBaseID: SPCC338.17C
• Length: 628
• Species: Schizosaccharomyces pombe
• Alignment Length: 794
• Identity: 197/794 - (24%)
• Similarity: 307/794 - (38%)
• Gaps: 259/794 - (32%)

  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGIL-QPKVKLALRTSGHLLLGVV 64
            |||...||:||||||::||||||:||::|.....|:||:||..|: :....:|||.||.|:||||
pombe     1 MFYSEAILSKKGPLAKVWLAAHWEKKLSKVQTLHTSIEQSVHAIVTEETAPMALRLSGQLMLGVV 65

  Fly    65 RIYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPE---------GHREANVNA-ITLPEVFHDFDT 119
            |||||||:|||.||.||.:::||:|:||.||:.|         |......:| :||||...:||.
pombe    66 RIYSRKARYLLEDCTEALMRLKMSFQPGQVDMIEPATALQSLKGKDAVTQSANLTLPETITEFDL 130

  Fly   120 ALPELNDIDIE-AQFSINQSRADE--------ITMREDYGSLSLSLQ-------DDGF------- 161
            .:|: :..|.: :|.....||:..        |:....:.|..||::       :.||
pombe   131 LVPD-STFDFQWSQLLRTPSRSSNTLELHSLPISSSPSFPSSQLSIEAGRNAQVESGFSLGESFA 194

  Fly   162 ---GDIGFE-------AETPEIIRCSIPSNINDKIFD----------NDVLENIESLDPHSLDAH 206
               .|:.|.       |.||..:.....|.|:.::..          :.::....:..|.|...|
pombe   195 HVGNDMQFHLPISNSGAATPRSVHSDNQSQISIEVGRDAPAAAATDLSGIIGPQMTKSPASSVTH 259

  Fly   207 ADMPGS-RLDGDGFGDSFGQPA------LFEDDLFGDPSQPVEQITKESTTVLNADDSDEDAIDN 264
            ...|.. .:.|....|....|.      |..|||.||          |......|.::||.|..:
pombe   260 FSTPSMLPIGGTSLDDELLAPVDDLNLDLGLDDLLGD----------EQGANAPAIEADEQAETS 314

  Fly   265 IHNVPSPATSLVNSIEDEKEENNLNGHASVSENVPMNEITLVQNEDEGFALAPLDVSMYKGVTKA 329
            ..::||      :.:||   :::....|.|.|...:...|..|.|    .:.|         .|.
pombe   315 SIHLPS------DIMED---DSSRPAAAGVEEGQVVESATAPQQE----KINP---------QKT 357

  Fly   330 KRKRKLIIDEIKNISGEEMKAQLADTSDILTTLDLAPPTKRLMYWKETGGVEKLFSLPSRSIPAR 394
            .|:::.|||.:..:|.::||.||||||.|.:.|                      .|.:.||...
pombe   358 VRRQRAIIDPVTELSSKQMKKQLADTSSITSPL----------------------CLNTSSIVFN 400

  Fly   395 ALF-----GNYNRQLFSHSTFFEDFSSVVPM--EILALEFYTKENENALIIFNKKGRKRKNDNMS 452
            |..     |.:|..:||        |::.|.  |:|..:|     :.|::      |||||::
pombe   401 ATVNFTRNGKFNTSIFS--------SNLNPKVNELLQADF-----KQAIL------RKRKNES-- 444

  Fly   453 NLFLDHVPDSVVQSLEAPEVLRANHKSLGVSTVSVEIVSKEQESISCQNELTFFDNMRSPDLLSL 517
                   |:         ||..|.|:....||       :.||:.    |:...:.:.:.:|.::
pombe   445 -------PE---------EVEPAKHQRTDTST-------ENQETA----EVLDPEEIAAAELANI 482

  Fly   518 NEMEQFSSINELPLTPRNMNHEMGD------------DFNQGDSTPAGLDHGHATPQHGNIGEMD 570
            .|....:...|..:.|.....|:|.            |.:..|:.|..||....      :|...
pombe   483 TEAAIATLPQETVVQPEGEAPELGSPMGFPVTALESADDSLFDAPPVMLDEADL------LGSER 541

  Fly   571 HDS----VIPTKKTAVILNESVGTSVLSDNGVSKRTNNILKGWDNYEIPSFVGQNHGDEQMENET 631
            .||    .:|:.:||                    .:::...||.|              .|.|
pombe   542 LDSSVSEALPSSQTA--------------------KDSLRNKWDPY--------------TEGE- 571

  Fly   632 DEQFEERVLNKRAAHLFIDVRAHFIAKDSLELSQLTSGNSRKQAAQKFYSLLVLKKFKVLHIDQS 696
                                        .:....|::|.:|::|.|.|:.:|||....|:.:.|.
pombe   572 ----------------------------KVSFQTLSAGCNREEAVQLFFDVLVLATKDVISVKQD 608

  Fly   697 -APYADITIT--RG 707
             |...:||:|  ||
pombe   609 VAIQNEITLTAKRG 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	59/111 (53%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	22/81 (27%)
		Rad21_Rec8	657..710	CDD:335912	17/54 (31%)
rad21	NP_588151.1	Rad21_Rec8_N	1..97	CDD:461446	56/95 (59%)
		Rad21_Rec8_M_SpRad21p-like	356..439	CDD:439290	30/123 (24%)
		Rad21_Rec8	568..623	CDD:335912	19/84 (23%)