Protein Alignment vtd and coh-1

DIOPT Version :9

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_509262.2
• Gene: coh-1 / 181003
• WormBaseID: WBGene00000591
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 758
• Identity: 208/758 - (27%)
• Similarity: 330/758 - (43%)
• Gaps: 218/758 - (28%)

  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVR 65
            |||...:|:|||||:::||||||:||::||.:|||:::::|..|:||..||||||:||||||:.|
 Worm     1 MFYADFVLSKKGPLSKVWLAAHWEKKLSKAQIFETDVDEAVNEIMQPSQKLALRTTGHLLLGICR 65

  Fly    66 IYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDF-DTALPELNDIDI 129
            :||||.|||||||||||:|||:.||.|.:|.|    ...:...::.:::.|| |..|||.::.::
 Worm    66 VYSRKTKYLLADCNEAFLKIKLVFRSGALDQP----NPVLPTFSIQDIYGDFGDNVLPEFDEEEL 126

  Fly   130 EAQFSINQSRADEITMRED--------YGSLSLSLQDDGFGDIGFEAETPEIIRCSIPSNINDKI 186
            . ...|.|||.|:||::||        ||.   .|:||.||:|.......:..|
 Worm   127 N-HAPICQSRLDDITLKEDIPQKFTYNYGE---PLEDDDFGEIAAGVGPEDYYR----------- 176

  Fly   187 FDNDVLENIESLD------------------------PHSLDAHADMPGSRLDGDGFGDSFGQPA 227
                ::|::..:|                        |...||||  ||:.:.||   :.|....
 Worm   177 ----LMEDVNKMDLEMELARDAATTSDNLFGREREPTPFLNDAHA--PGNAIFGD---EDFAGGD 232

  Fly   228 LFEDD--------LFGDPSQPVEQITKES-TTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEK 283
            :.:||        ...:.:..:|.:..|| .|::..:........|....||||.|:.
 Worm   233 MDDDDHNVQGSSGFTDNNAMHMEDMDYESGNTMMRGETPLRSDTPNTFRAPSPAPSIA------- 290

  Fly   284 EENNLNGHASVSENVPMNEITLVQNEDEGFALAPLDVSMYKGVTKAKRKRKLIIDEIKNISGEEM 348
                    .||:.:|...|...:::..|..|       ..:.:.|.:..||..:|::|.|:||||
 Worm   291 --------PSVATSVSAMEHDTIESYYERQA-------QKRAMQKEQNMRKRRVDDVKMITGEEM 340

  Fly   349 KAQLADTSDILTTLDLAPPTKRLMYWKETGGVEKLFSLPSRSIPARALFG-NYNRQLFSHSTFFE 412
            |..:||.|||||.||||||:::||..|:....|.:...|       .:.| :.|:|
 Worm   341 KGNMADFSDILTRLDLAPPSRKLMMGKKRSHAEYMHHNP-------GMIGFSKNKQ--------- 389

  Fly   413 DFSSVVPMEILALEFYTKENENALIIFNKKGRKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRANH 477
                           :.::.::.|::........||:.:.|
 Worm   390 ---------------FIRKYQSYLVVTKHDDVDEKNEWIKN------------------------ 415

  Fly   478 KSLGVSTVSVEIVSKEQESIS--CQNELTFFDNMRSPDLLSLNEMEQFSSINELPLTPRNMNHEM 540
             :||:..:..|.:.::|:.:.  .|::.::.|:......|..::::...       .|::|
 Worm   416 -ALGLREIGEEELQQQQQEMDMHVQDDSSYVDDFDEVPPLDFDQLDMMD-------MPQSM---- 468

  Fly   541 GDDFNQGDSTPAGLDHGHATPQHGNIGE----MDHDSVIPTKKTAVILNESVGTSVLSDNGVSKR 601
             ||.|..|..         .||...:..    ::.:.:.|::|......|........||..|||
 Worm   469 -DDINMVDDD---------VPQRNPLSPFAPMVEDEEMSPSEKRKKRDEEKEEPETDEDNRWSKR 523

  Fly   602 TNNILKGWDNYEIPSFVGQNHGDEQMENETDEQFEERVLNKRAAHLFIDVRAHFIAKDSLELSQ- 665
            |:.:|             ||.. .::||:..:                           :||.:
 Worm   524 THALL-------------QNIA-TKLENQNGQ---------------------------VELDEM 547

  Fly   666 LTSGNSRKQAAQKFYSLLVLKKFKVLHIDQSAPYADITITRGP 708
            |..|.|||.||.||||||.|||.:.:.|:|..||.||.|..||
 Worm   548 LKKGTSRKVAAAKFYSLLCLKKNQCIDIEQKEPYGDIMIKAGP 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..106	CDD:282655	62/104 (60%)
		Rad21_Rec8	657..710	CDD:282654	27/53 (51%)
coh-1	NP_509262.2	Rad21_Rec8_N	1..97	CDD:368143	61/95 (64%)
		Rad21_Rec8	539..591	CDD:335912	27/79 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I2880
eggNOG	1	0.900	-	-		E1_KOG1213
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253899at2759
OrthoFinder	1	1.000	-	-		FOG0001363
OrthoInspector	1	1.000	-	-		oto20249
orthoMCL	1	0.900	-	-		OOG6_103388
Panther	1	1.100	-	-	LDO	PTHR12585
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1093
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.780