Protein Alignment vtd and scc-1

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_494836.1
• Gene: scc-1 / 173808
• WormBaseID: WBGene00004737
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 758
• Identity: 217/758 - (28%)
• Similarity: 332/758 - (43%)
• Gaps: 177/758 - (23%)

  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVR 65
            |||...:||||||||::||||||:||:|||.:|||::.:::|.:::||||:||||.||||||:||
 Worm     1 MFYAQFVLAKKGPLAKVWLAAHWEKKLTKAQIFETDVPQAIEEVIRPKVKMALRTVGHLLLGIVR 65

  Fly    66 IYSRKAKYLLADCNEAFVKIKMAFRPGM---VDLPEGHREANVNAITLPEVFHDF----DTALPE 123
            |||:|.:|||||.|||:.|:|:.||.|.   ||:||       || .:.|.|.:|    :..:||
 Worm    66 IYSKKTRYLLADTNEAYQKMKINFRNGFSFEVDIPE-------NA-EIEEDFSNFIDKYNITVPE 122

  Fly   124 LNDIDIEAQFSI-NQSRADEITMREDYG---SLSLSLQDDGFGDIGFEAE--------------- 169
            .:|.|...|..: |.||.::|||:|...   ..::....|||||.|...:
 Worm   123 FHDADYNEQLIMANVSRREDITMKETVNFNVEFNIDADFDGFGDEGESWQLDHLYGSVEPLSLRP 187

  Fly   170 TPEIIRCSIPSNINDKIFDNDVLENIESLDPHSLDAHADMPGSRLDGDG--FGDSFGQPALFEDD 232
            ||:      |.::.:...|.||..|...:             ||:|.|.  |.:...:|.|..|:
 Worm   188 TPQ------PESLMEVERDRDVAANGTEI-------------SRIDADSVIFSEGPTRPNLIFDN 233

  Fly   233 LFGDPSQPVEQITKESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHASVSEN 297
            ..|....|...:..|:.|:.|  |......|...::..|...  :::.|.:.::.::......|
 Worm   234 QEGGNFMPEMNLKVENQTLEN--DGGVGPADMFSSMIHPVRE--HAVADVQNDDGMDFDYQPFE- 293

  Fly   298 VPMNEITLVQNEDEGFALAPLDVSMYKGVTKAKRK-RKLIIDEIKNISGEEMKAQLADTSDILTT 361
             |.|.........|.|||.||||...:|..|.:|| ||||:|....||.:..:.|..|.||.:..
 Worm   294 -PENVEPSRPQSPESFALEPLDVEHMEGRKKRQRKARKLIVDAETMISNDAFREQQEDFSDTMRV 357

  Fly   362 LDLAPPTKRLMYWKETGGVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVPMEILALE 426
            :::||||:::.....:|.::.|...|...:..|.|...|.|.|.:.                  |
 Worm   358 VEMAPPTRKMFNLCVSGDLQHLSREPGCKMFNRELLQRYRRCLVTR------------------E 404

  Fly   427 F---YTKENENALIIFNKKGRKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRANHKSLGVSTVSVE 488
            |   ||.:              ..:|:.|     ..|....|: |..|.|..|...
 Worm   405 FDLNYTMQ--------------ELSDSSS-----FTPSMEAQA-EPWEDLNLNEDI--------- 440

  Fly   489 IVSKEQESISCQNELT--FFDNMRSPDLLSLNEMEQFSSINELPLTPRNMNHEMGDDFNQGDSTP 551
                 ||.|..|....  ||:::|      :::.:......|:         :.||:|:    .|
 Worm   441 -----QEDIQAQGPAVDEFFNDVR------MDDDDDRQPAQEM---------DFGDNFD----FP 481

  Fly   552 AGLDHGHATP---QHGNIGEMDHDSVIPTKKTAVILNESVGTSVLSDNGVSKRTNNILKGWDNYE 613
            ..::|....|   |.|..||...:      :.|...::..|:|..|..|               :
 Worm   482 QEVEHQECAPIPIQSGFAGENKEN------EDAEDWSDPFGSSNSSRRG---------------Q 525

  Fly   614 IPSFVGQNHGDEQMENETDEQFEERVLNKRAAHLFIDVRAHFIAKDSLELSQLT-SGNSRKQAAQ 677
            :.::   ..|:.....|.|.::.     |||.|:...|.|........:.|.:| :..:|||||:
 Worm   526 LEAY---GFGNTSTYKEDDGKWA-----KRAKHILKKVSADIETSGQADFSSVTATAKNRKQAAE 582

  Fly   678 KFYSLLVLKKFKVLHIDQSAPYADITITRGPTFE------NPK 714
            :|||||.|.|.:.:.:|||.||.:|.|..|..|:      :||
 Worm   583 QFYSLLTLAKSQAISVDQSEPYGEIVIRPGANFKEACPLSSPK 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	63/104 (61%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	25/77 (32%)
		Rad21_Rec8	657..710	CDD:335912	22/53 (42%)
scc-1	NP_494836.1	Rad21_Rec8_N	1..103	CDD:461446	63/108 (58%)
		Rad21_Rec8_M_NXP1-like	331..403	CDD:439294	21/71 (30%)
		Rad21_Rec8	561..615	CDD:335912	22/53 (42%)