Protein Alignment vtd and rad21

DIOPT Version :10

• Sequence 1: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_031759353.1
• Gene: rad21 / 100492023
• XenbaseID: XB-GENE-1008099
• Length: 631
• Species: Xenopus tropicalis
• Alignment Length: 757
• Identity: 286/757 - (37%)
• Similarity: 395/757 - (52%)
• Gaps: 176/757 - (23%)

  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVR 65
            |||.|.:|:|:||||:||||||||||:|||||||.|:|.|||.|:.||||:||||||||||||||
 Frog     1 MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVR 65

  Fly    66 IYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDFDTALPELNDIDIE 130
            ||.||||||||||||||:|||||||||:|||||.:|||..|||||||.|||||..||:|:|||:.
 Frog    66 IYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVA 130

  Fly   131 AQFSINQSRADEITMREDYGSLSLSLQDDGFGDIGFEAETPEIIRCSIPSNINDKIFDNDVLENI 195
            .|||:||||.:||||||:..:::: |||:.|||.|.:..  |::|       ....|::|:|...
 Frog   131 QQFSLNQSRVEEITMREEVSNINI-LQDNDFGDFGMDDR--EMMR-------EGSAFEDDMLTTS 185

  Fly   196 ES---LDPHSLDAHADMPGSRLDGDG--FGDSFGQ--------PALFEDD---LFGD-PSQPVEQ 243
            .|   |:|....:..:...:.|:.|.  ..|:||:        ..|..:|   :|.| |:.|.|.
 Frog   186 ASNLLLEPEQSTSQLNEKSNHLEYDDQYKDDNFGEGNDGGILDDKLLSNDAGGIFDDPPAMPEEG 250

  Fly   244 ITKESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHASVSENVPM----NEIT 304
            :......|  .||.|:|  ||:......:...|:.:|                  |:    ::.|
 Frog   251 VAMPEQPV--HDDLDDD--DNVSMGAPDSPDSVDPVE------------------PLPTMTDQTT 293

  Fly   305 LVQNEDEGFALAPLDVSMYKGVTKAKRKRKLIIDEIKNISGEEMKAQLADTSDILTTLDLAPPTK 369
            ||.||:|.|||.|:|:::.:  ||||||||||:|.:|.:..:.::|||:|.|||:||||||||||
 Frog   294 LVPNEEEAFALEPIDITVKE--TKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTK 356

  Fly   370 RLMYWKETGGVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVPMEILALEFYTKENEN 434
            :||.||||||||||||||::.:        :|.:|.  ..|....:.:||.::
 Frog   357 KLMMWKETGGVEKLFSLPAQPL--------WNSRLL--KLFTRCLTPLVPEDL------------ 399

  Fly   435 ALIIFNKKGRKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRANHKSLGVSTVSV-EIVSKEQESIS 498
                  ||  :||.....||      |..::..|.|||.|...:...|....: |..|:.|||:
 Frog   400 ------KK--RRKGGEADNL------DEFLKEFENPEVPREELRPQDVIDQPILEEASRLQESL- 449

  Fly   499 CQNELTFFDNMRSP----------DLLSLNE-----MEQFSSINELPLTPRNMNHEMGDDFNQGD 548
            .:...|..|....|          |.|.:..     |::.....|:|..|.....|:..:.::
 Frog   450 MEGSRTHLDETIMPPPPPQQGVKRDSLQMEPEPVPVMQETEPHIEMPPPPLPPPVELPSEVSE-- 512

  Fly   549 STPAGLDHGHATPQHGNIGEMDHD-SVIPTKKTAVILNESVGTSVLSDNGVSKRTNNILKGWDNY 612
                       ||   ||.::..: :::|.|
 Frog   513 -----------TP---NINDLIPELNLLPEK---------------------------------- 529

  Fly   613 EIPSFVGQNHGDEQMENE------TDEQFEERVLNKRAAHLFIDVRAHFIAK---DSLELSQLTS 668
                   :...||:.|.|      |::..|||..|||...:...:: ..:||   :|:.|..|..
 Frog   530 -------EKEKDEEEEEEEEDATGTEQDQEERRWNKRTQQMLHGLQ-RVLAKTGAESISLLDLCR 586

  Fly   669 GNSRKQAAQKFYSLLVLKKFKVLHIDQSAPYADITITRGPTF 710
            ..:|||||.||||.|||||.:.:.:.|:.||:||..|.||.|
 Frog   587 NTNRKQAAAKFYSFLVLKKQQAIELTQAEPYSDIIATPGPRF 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	82/101 (81%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	46/76 (61%)
		Rad21_Rec8	657..710	CDD:335912	27/55 (49%)
rad21	XP_031759353.1	Rad21_Rec8_N	1..104	CDD:461446	83/102 (81%)
		Rad21_Rec8_M_NXP1-like	314..393	CDD:439294	48/88 (55%)
		Rad21_Rec8	574..628	CDD:335912	25/53 (47%)