Protein Alignment rl and Cilk1

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_620241.1
• Gene: Cilk1 / 84411
• RGDID: 71050
• Length: 629
• Species: Rattus norvegicus
• Alignment Length: 305
• Identity: 108/305 - (35%)
• Similarity: 164/305 - (53%)
• Gaps: 36/305 - (11%)

  Fly    37 RYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHENIIDIR 100
            ||..:..:|:|.||.|:......:.:.:||||:. .|.....|. .|||:..|.:..|.||:.::
  Rat     3 RYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECM-NLREVKSLKKLNHANIVKLK 66

  Fly   101 DILRVDSIDQMRDVYIVQCLMETDLYKLLKTQR--LSNDHICYFLYQILRGLKYIHSANVLHRDL 163
            :::|.:.     .:|.:...|:.:||:|:|.:.  .....|...:||||:||.:||.....||||
  Rat    67 EVIREND-----HLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDL 126

  Fly   164 KPSNLLLNKTCDLKICDFGLAR--IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWS 226
            ||.|||......:||.||||||  .:.|.:      |:||:||||||||::|.|..|:..||:|:
  Rat   127 KPENLLCMGPELVKIADFGLAREIRSRPPY------TDYVSTRWYRAPEVLLRSTNYSSPIDVWA 185

  Fly   227 VGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDL-ECIINEKARNYLESLPFKPNVPWAK 290
            ||||:||:.:.||:|||...:|.:..|..|||:|.:.|. |......|.|::          |.:
  Rat   186 VGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFI----------WPQ 240

  Fly   291 --------LFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLE 327
                    |.|||.:.|:.||..:|.::|.||....:||.:||.:
  Rat   241 CIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQ 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	108/305 (35%)
Cilk1	NP_620241.1	STKc_MAK_like	4..284	CDD:270824	106/301 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..322
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..482
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..629