DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rl and MPK15

DIOPT Version :9

Sequence 1:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_565070.2	Gene:	MPK15 / 843702	AraportID:	AT1G73670	Length:	576	Species:	Arabidopsis thaliana

Alignment Length:	366	Identity:	163/366 - (44%)
Similarity:	234/366 - (63%)	Gaps:	24/366 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VVNGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISP-FE 73
            :.|....||..::|    |.||.||         :|:|:||:|.||.||.|.:|||||||:. |:
plant    75 IPNAEFFTEYGEAN----RYQIQEV---------VGKGSYGVVGSAIDTHTGERVAIKKINDVFD 126

  Fly    74 HQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLK-TQRLSND 137
            |.:...|.||||.:|....|.::::|:.|:...|..:.||||:|..|||:||::::| ...|:.:
plant   127 HISDATRILREIKLLRLLLHPDVVEIKHIMLPPSRREFRDVYVVFELMESDLHQVIKANDDLTPE 191

  Fly   138 HICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVA 202
            |..:||||:||||||:|:|||.||||||.|:|.|..|.||||||||||::..:.....|.|:|||
plant   192 HHQFFLYQLLRGLKYVHAANVFHRDLKPKNILANADCKLKICDFGLARVSFNDAPTAIFWTDYVA 256

  Fly   203 TRWYRAPEI--MLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDL 265
            ||||||||:  ...|| ||.:|||||||||.||||..:|:||||:.:.||:.:...||:|..:.:
plant   257 TRWYRAPELCGSFFSK-YTPAIDIWSVGCIFAEMLLGKPLFPGKNVVHQLDIMTDFLGTPPPEAI 320

  Fly   266 ECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYL---- 326
            ..|.|:|||.||.::..|..||::|.||.||..||.||.:::.|:|..|...|||||.||.
plant   321 SKIRNDKARRYLGNMRKKQPVPFSKKFPKADPSALRLLERLIAFDPKDRPSAEEALADPYFNGLS 385

  Fly   327 EQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKF 367
            .:..:|..:|::::.|  ..|...:::|.::.||:.|.|::
plant   386 SKVREPSTQPISKLEF--EFERKKLTKDDIRELIYREILEY 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	155/341 (45%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	144/291 (49%)
MPK15	NP_565070.2	STKc_TDY_MAPK	89..426	CDD:143364	159/348 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.780