DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rl and MPK4

DIOPT Version :9

Sequence 1:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_192046.1	Gene:	MPK4 / 828151	AraportID:	AT4G01370	Length:	376	Species:	Arabidopsis thaliana

Alignment Length:	368	Identity:	179/368 - (48%)
Similarity:	242/368 - (65%)	Gaps:	8/368 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FNSSGSVVNGTGSTEVPQSNAEV-IRGQIFEVGPRYI-KLAYIGEGAYGMVVSADDTLTNQRVAI 66
            |.|||...:..|......|..:. :.|.:|||..:|: .|..||.||||:|.:|.::.|.:.|||
plant     7 FGSSGDQSSSKGVATHGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAI 71

  Fly    67 KKI-SPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLK 130
            ||| :.|::....:||||||.:|....|||:|.::||::....:...|||||..||:|||:::::
plant    72 KKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIR 136

  Fly   131 T-QRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHT 194
            : |.|::||..:||||:||||||:||||||||||||||||||..||||:.||||||    ....|
plant   137 SNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLAR----TKSET 197

  Fly   195 GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGS 259
            .|:||||.||||||||::||...||.:||||||||||.|.::..|:||||.|:.||..|..::||
plant   198 DFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGS 262

  Fly   260 PSRDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHP 324
            |....|..:.::.||.|:..||..|...:|..|||..|.|:|||.|||.|:|.:||.|:|||.||
plant   263 PDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALCHP 327

  Fly   325 YLEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKF 367
            ||...:|..:|||...||..:.|...::.:.:|.||:.||:||
plant   328 YLAPLHDINEEPVCVRPFNFDFEQPTLTEENIKELIYRETVKF 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	170/336 (51%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	153/290 (53%)
MPK4	NP_192046.1	STKc_TEY_MAPK	36..372	CDD:143363	172/339 (51%)
MPK4	NP_192046.1	S_TKc	46..329	CDD:214567	152/286 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	349	1.000	Inparanoid score	I618
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	1	1.000	-	-		otm2432
orthoMCL	1	0.900	-	-		OOG6_100339
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X259
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.730