DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rl and Mapk11

DIOPT Version :9

Sequence 1:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_017450608.1	Gene:	Mapk11 / 689314	RGDID:	1309340	Length:	371	Species:	Rattus norvegicus

Alignment Length:	355	Identity:	164/355 - (46%)
Similarity:	230/355 - (64%)	Gaps:	16/355 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 IFEVGPRYIKLAYIGEGAYGMV-------VSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITI 87
            ::||..|...|..:|.||||.|       .||.|....|:||:||:| ||:...:.:||.||:.:
  Rat    17 VWEVPQRLQGLRPVGSGAYGSVWSHPGPPHSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRL 81

  Fly    88 LTRFKHENIIDIRDILR-VDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLK 151
            |...||||:|.:.|:.. ..||:...:||:|..||..||..::|.|.||::|:.:.:||:|||||
  Rat    82 LKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLK 146

  Fly   152 YIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSK 216
            |||||.::||||||||:.:|:.|:|:|.||||||.||.|      :|.|||||||||||||||..
  Rat   147 YIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEE------MTGYVATRWYRAPEIMLNWM 205

  Fly   217 GYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLP 281
            .|.:::||||||||:||:|..:.:|||..|:|||..|:.|:|:||.:.|..|.:|.||.|::|||
  Rat   206 HYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLP 270

  Fly   282 FKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINM 346
            ..|....:.:|..|:.||:||||:||..:..:|:...|||||.|..||:||.|||.|| |:..::
  Rat   271 PMPQKDLSSVFHGANPLAVDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAE-PYDESV 334

  Fly   347 ENDDISRDALKSLIFEETLKFKERQPDNAP 376
            |..:.:.:..|.|.::|.|.||..:....|
  Rat   335 EAKERTLEEWKELTYQEVLSFKPLETSQLP 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	160/342 (47%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	142/296 (48%)
Mapk11	XP_017450608.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810