Protein Alignment rl and MAPK7

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_006721620.1
• Gene: MAPK7 / 5598
• HGNCID: 6880
• Length: 822
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 176/370 - (47%)
• Similarity: 243/370 - (65%)
• Gaps: 14/370 - (3%)

  Fly    16 STEVPQSNAEVIRGQ----IFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKI-SPFEHQ 75
            :..|...|..:::.:    .|:||..|..:..||.||||:|.||...||.|:|||||| :.|:..
Human    29 AASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVV 93

  Fly    76 TYCQRTLREITILTRFKHENIIDIRDILR-------VDSIDQMRDVYIVQCLMETDLYKLL-KTQ 132
            |..:|||||:.||..|||:|||.|:||||       ..|:......|:|..|||:||:::: .:|
Human    94 TNAKRTLRELKILKHFKHDNIIAIKDILRPTVPYGEFKSVPYGVPGYVVLDLMESDLHQIIHSSQ 158

  Fly   133 RLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLAR-IADPEHDHTGF 196
            .|:.:|:.|||||:||||||:|||.|:||||||||||:|:.|:|||.|||:|| :.....:|..|
Human   159 PLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYF 223

  Fly   197 LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPS 261
            :|||||||||||||:||:...||::||:||||||..|||:.|.:||||:|:.||..|:.|||:||
Human   224 MTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPS 288

  Fly   262 RDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYL 326
            ...::.:..|:.|.|::|||.:..|||..::|.||..||.|||:||.|.|..||....||.||:|
Human   289 PAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFL 353

  Fly   327 EQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKFKERQ 371
            .:|:||.|||....||....:.:.::|:.:|..|..|...|..|:
Human   354 AKYHDPDDEPDCAPPFDFAFDREALTRERIKEAIVAEIEDFHARR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	172/343 (50%)
MAPK7	XP_006721620.1	STKc_ERK5	49..390	CDD:270842	171/340 (50%)