Protein Alignment rl and mapk12b

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001038306.1
• Gene: mapk12b / 557810
• ZFINID: ZDB-GENE-041210-123
• Length: 364
• Species: Danio rerio
• Alignment Length: 344
• Identity: 151/344 - (43%)
• Similarity: 214/344 - (62%)
• Gaps: 9/344 - (2%)

  Fly    27 IRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKI-SPFEHQTYCQRTLREITILTR 90
            |...:::|..||..|..||.||||.|.||.|..|..||||||: .||:.:.:.:|..||:.:|..
Zfish    14 INRTVWDVPERYRDLIQIGTGAYGTVCSAIDRKTGVRVAIKKLHRPFQSRLFAKRAYRELRLLKH 78

  Fly    91 FKHENIIDIRDILRVD-SIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIH 154
            .||||:|.:.|:...: .:|:..|.|:|...|.|||.||:|.:||..|.:.:.:|||||||||||
Zfish    79 MKHENVIGLLDVFTSEILLDRFHDFYLVMPFMGTDLGKLMKMERLCEDRVQFLVYQILRGLKYIH 143

  Fly   155 SANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYT 219
            ||.::||||||.||.:|:.|:|||.||||||.||.|      :|.||.||||||||::||...|:
Zfish   144 SAGIIHRDLKPGNLAVNQNCELKILDFGLARQADSE------MTGYVVTRWYRAPEVILNWMHYS 202

  Fly   220 KSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKP 284
            :::||||||||:||||..|.:|.|..:||||..|:.:.|:|:.|.:..:.::.|:||:..||..|
Zfish   203 QTVDIWSVGCIMAEMLLGRTLFKGNDHLDQLREIMKITGTPAPDFITKLQSQDAKNYIRGLPKVP 267

  Fly   285 NVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMEND 349
            ......:|..|.:.|:..|..||..:|.||:...|||..|...::.:|.:|..| :|:..:|:|.
Zfish   268 KKDLNTIFFKASSEAVSALELMLVLDPDKRVSAAEALELPLFTEFREPEEETEA-LPYDHSMDNT 331

  Fly   350 DISRDALKSLIFEETLKFK 368
            ::..|..|...|.|.|.|:
Zfish   332 ELPLDQWKRHTFTEILSFQ 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	148/335 (44%)
mapk12b	NP_001038306.1	Protein Kinases, catalytic domain	9..351	CDD:473864	151/344 (44%)