Protein Alignment rl and Mapk10

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001305119.1
• Gene: Mapk10 / 25272
• RGDID: 3663
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 389
• Identity: 148/389 - (38%)
• Similarity: 238/389 - (61%)
• Gaps: 39/389 - (10%)

  Fly     2 EEFNSSGSVV-NGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVA 65
            :.:|.|.|.| |...|.||..|...|::        ||..|..||.||.|:|.:|.|.:.::.||
  Rat    35 KHYNMSKSKVDNQFYSVEVGDSTFTVLK--------RYQNLKPIGSGAQGIVCAAYDAVLDRNVA 91

  Fly    66 IKKIS-PFEHQTYCQRTLREITILTRFKHENIIDIRDILRVD-SIDQMRDVYIVQCLMETDLYKL 128
            |||:| ||::||:.:|..||:.::....|:|||.:.::.... ::::.:|||:|..||:.:|.::
  Rat    92 IKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQV 156

  Fly   129 LKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDH 193
            ::.: |.::.:.|.|||:|.|:|::|||.::||||||||:::...|.|||.||||||.|.
  Rat   157 IQME-LDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAG----- 215

  Fly   194 TGF-LTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVL 257
            |.| :|.||.||:|||||::| ..||.:::||||||||:.||:.::.:|||:.|:||.|.::..|
  Rat   216 TSFMMTPYVVTRYYRAPEVIL-GMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQL 279

  Fly   258 GSPSRDDLECIINEKARNYLESLPFKPNVPWAKLFPN----AD--------ALALDLLGKMLTFN 310
            |:|..:.:: .:....|||:|:.|....:.:.||||:    ||        :.|.|||.|||..:
  Rat   280 GTPCPEFMK-KLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVID 343

  Fly   311 PHKRIPVEEALAHPYLEQYYDPGDEPVAEVP----FRINMENDDISRDALKSLIFEETLKFKER 370
            |.|||.|::||.|||:..:|||.:   .|.|    :...::..:.:.:..|.||::|.:..:|:
  Rat   344 PAKRISVDDALQHPYINVWYDPAE---VEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEK 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	137/352 (39%)
Mapk10	NP_001305119.1	STKc_JNK	63..398	CDD:270840	136/345 (39%)