Protein Alignment rl and Cdk10

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_919428.1
• Gene: Cdk10 / 234854
• MGIID: 2448549
• Length: 360
• Species: Mus musculus
• Alignment Length: 346
• Identity: 115/346 - (33%)
• Similarity: 174/346 - (50%)
• Gaps: 62/346 - (17%)

  Fly    18 EVPQSNAEVIRGQ-IFEVGP-----------RYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS 70
            |..|...:.||.: .|.|.|           .:.||..||||.||:|..|.||.|::.||:||:.
Mouse     7 ESDQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVR 71

  Fly    71 --------PFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYK 127
                    |..       :|||||:|.|.:|.||:::::::..:.::   .:::|....|.||..
Mouse    72 MDKEKDGIPIS-------SLREITLLLRLRHPNIVELKEVVVGNHLE---SIFLVMGYCEQDLAS 126

  Fly   128 LLKTQ--RLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLL-NKTCDLKICDFGLARI--- 186
            ||:..  ..|...:...:.|:||||:|:|...::|||||.||||: :|.| :|..||||||.
Mouse   127 LLENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGC-VKTADFGLARAYGV 190

  Fly   187 -ADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQL 250
             ..|       :|..|.|.||||||::|.:...|.|||:|:|||||||:|:::|:.||...:.|:
Mouse   191 PVKP-------MTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQI 248

  Fly   251 NHILGVLGSPSRDDLECIINEKARNYLESLPFKPNV-----PWAKL---FPNADALALDLLGKML 307
            :.|:.:||:||         |........||.....     |:..|   ||......|.||..:.
Mouse   249 DLIVQLLGTPS---------ENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLLNFLF 304

  Fly   308 TFNPHKRIPVEEALAHPYLEQ 328
            .::|.||....:.|...|.::
Mouse   305 MYDPKKRATSGDCLESSYFKE 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	111/331 (34%)
Cdk10	NP_919428.1	STKc_CDK10	31..339	CDD:173742	108/322 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	334..360