Protein Alignment rl and kgb-2

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_500384.2
• Gene: kgb-2 / 191169
• WormBaseID: WBGene00002188
• Length: 332
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 127/318 - (39%)
• Similarity: 184/318 - (57%)
• Gaps: 32/318 - (10%)

  Fly    29 GQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKI-SPFEHQTYCQRTLREITILTRFK 92
            |..|.:..||:.|.::..||.|:||.|||.:|.|||||||: .||......:|..||..:||..|
 Worm    20 GITFTIPTRYVNLKFLNVGAQGIVVMADDLVTTQRVAIKKMQQPFLLTMSARRAYREFILLTTLK 84

  Fly    93 HENIIDIRDILRVD-SIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSA 156
            |.|||.:.:....| |:...::||:|...|..:|::::...||.::.:.:.:||.|..:|::|:.
 Worm    85 HPNIIRLLNAFTPDTSLSSFQEVYLVMEFMTHNLHEVIHRLRLDHETLSFLVYQSLCAIKHLHNL 149

  Fly   157 NVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKS 221
            ..:||||||||:::|:.|.||:.||||||..:.:..    :::||.||:|||||::| ...|::.
 Worm   150 GFIHRDLKPSNIVVNERCVLKVLDFGLARRRNVDMR----MSDYVGTRYYRAPEVIL-GLNYSEK 209

  Fly   222 IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDD-----LECIINEKARNYLESLP 281
            :||||||||||||:::..:||||...||...|..||.:|  ||     ||.|    ...|:.|||
 Worm   210 VDIWSVGCILAEMINHTVLFPGKDIRDQWTQISSVLRTP--DDHFINQLEPI----GAVYVRSLP 268

  Fly   282 ------FKPNVPWAKLFPNAD--------ALALDLLGKMLTFNPHKRIPVEEALAHPY 325
                  |...||.:...|..:        .:|.|||..||..||.:|..||:||.|||
 Worm   269 QHLARAFNEIVPDSNFLPETENPKDHLTLHMARDLLFNMLKINPEERYSVEDALNHPY 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	126/315 (40%)
kgb-2	NP_500384.2	Protein Kinases, catalytic domain	28..329	CDD:473864	125/310 (40%)