Protein Alignment rl and Mapk11

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_035291.4
• Gene: Mapk11 / 19094
• MGIID: 1338024
• Length: 364
• Species: Mus musculus
• Alignment Length: 348
• Identity: 165/348 - (47%)
• Similarity: 231/348 - (66%)
• Gaps: 9/348 - (2%)

  Fly    31 IFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHE 94
            ::||..|...|..:|.||||.|.||.|....|:||:||:| ||:...:.:||.||:.:|...|||
Mouse    17 VWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81

  Fly    95 NIIDIRDILR-VDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANV 158
            |:|.:.|:.. ..||:...:||:|..||..||..::|.|.||::|:.:.:||:||||||||||.:
Mouse    82 NVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGI 146

  Fly   159 LHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSID 223
            :||||||||:.:|:.|:|:|.||||||.||.|      :|.|||||||||||||||...|.:::|
Mouse   147 IHRDLKPSNVAVNEDCELRILDFGLARQADEE------MTGYVATRWYRAPEIMLNWMHYNQTVD 205

  Fly   224 IWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPW 288
            |||||||:||:|..:.:|||..|:|||..|:.|:|:||.:.|..|.:|.||.|::|||..|....
Mouse   206 IWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDL 270

  Fly   289 AKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISR 353
            :.:|..|:.||:||||:||..:..:|:...|||||.|..||:||.|||.|| |:..::|..:.:.
Mouse   271 SSVFHGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPDDEPEAE-PYDESVEAKERTL 334

  Fly   354 DALKSLIFEETLKFKERQPDNAP 376
            :..|.|.::|.|.||..:|...|
Mouse   335 EEWKELTYQEVLSFKPLEPSQLP 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	160/335 (48%)
Mapk11	NP_035291.4	Protein Kinases, catalytic domain	8..350	CDD:473864	162/339 (48%)
		TXY	180..182		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..331		9/19 (47%)