Protein Alignment rl and sma-5

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001391190.1
• Gene: sma-5 / 181373
• WormBaseID: WBGene00004859
• Length: 521
• Species: Caenorhabditis elegans
• Alignment Length: 420
• Identity: 133/420 - (31%)
• Similarity: 219/420 - (52%)
• Gaps: 71/420 - (16%)

  Fly     4 FNSSGSVVNGTGSTEVP-----QSNA--------------EVIRG----------QIFEVGPRYI 39
            ||::.:.....||.|.|     |:|.              .|:.|          ::......|.
 Worm    42 FNTNPTNGKSRGSQEAPRKPLGQTNLNVQGSMPAKKEGFNRVLDGLKKRQLQHDFKLERAAETYE 106

  Fly    40 KLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEH----QTYCQRTLREITILTRFKHENIIDIR 100
            ....||.||:|:|..|.:|.:||:|||||::   |    .|..:||||||.:|....|.||:.:|
 Worm   107 PTQNIGSGAFGIVCEAVETSSNQKVAIKKVA---HASATPTLARRTLREIRVLRYINHPNIVPLR 168

  Fly   101 DILRVDSIDQMRDVYIVQCLMETDLYKLL--KTQRLSNDHICYFLYQILRGLKYIHSANVLHRDL 163
            ||.|......: ||::|..||:.:|:.::  ....|...:|..||.|:||||:|:|:|.:.||||
 Worm   169 DIFRTKGPLGI-DVFLVMDLMQNNLHHIIYGNEDPLEEHYINAFLGQLLRGLEYLHAACIAHRDL 232

  Fly   164 KPSNLLLNKTCDLKICDFGLARIAD---PEHD---HTGFLTEYVATRWYRAPEIMLNSKGYTKSI 222
            ||||||:|:...|:|.|||:|:.||   .:||   |..::|::|||..|||||::.....::.::
 Worm   233 KPSNLLVNQDGTLRIADFGMAKCADNSSKKHDDEEHCYYMTQHVATLPYRAPELLFVLPEHSTAV 297

  Fly   223 DIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINE----KARNYLESLPFK 283
            |:|:||||..||:....|.||:....|:..:|.:||.|.::    :|||    :.|..::....|
 Worm   298 DMWAVGCIFGEMVIRNEILPGRSVQGQIKMLLTMLGQPPQE----VINEVRCDRTRKLIQDFGRK 358

  Fly   284 PNVPWAKLF------------PNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEP 336
            .:..|..:.            .|.|  .:|.:.::..::..|||.:::||.|||:::.. |.:.|
 Worm   359 ADAEWDDIMFCKARGDDQIVRGNCD--TIDFVKQLFQYDAQKRINIQDALLHPYIQRVI-PAEAP 420

  Fly   337 VAEVPFRIN---MENDDISRDALKSLIFEE 363
            ..:.|||:.   |:.:|::...|.|::.::
 Worm   421 QKKCPFRVKKDMMQVEDLNHQELISMMKQD 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	123/363 (34%)
sma-5	NP_001391190.1	STKc_ERK5	102..446	CDD:270842	122/354 (34%)