Protein Alignment rl and pmk-3

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001379550.1
• Gene: pmk-3 / 177610
• WormBaseID: WBGene00004057
• Length: 474
• Species: Caenorhabditis elegans
• Alignment Length: 368
• Identity: 138/368 - (37%)
• Similarity: 200/368 - (54%)
• Gaps: 52/368 - (14%)

  Fly    32 FEVGPRYIKLAYIGEGAYGMVVSAD----DTLTNQRVAIKKI-SPFEHQTYCQRTLREITILTRF 91
            ::|.|..|:  |:|.|::|.|:...    |.| .:.|||||: .||....:.:|..||..:|...
 Worm   114 YDVEPNSIE--YLGGGSFGNVIKTSAVCRDGL-RRYVAIKKMREPFFDPHHARRIFRETKLLQLM 175

  Fly    92 KHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQR------LSNDHICYFLYQILRGL 150
            :|:|||...||...|..:..||||:|.......||::||.||      |:::||.:.:|||:|.|
 Worm   176 RHDNIICALDIYTPDEENDFRDVYVVTEFAGRSLYQILKQQRDYGRRVLTDEHIKFIIYQIIRAL 240

  Fly   151 KYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIML-N 214
            |||||||::||||||.||.|....||.|.||||||..:.:...   ||:||.|||||:||::. .
 Worm   241 KYIHSANIIHRDLKPGNLALTDDSDLMILDFGLARSLEKKDTS---LTQYVQTRWYRSPEVIYWK 302

  Fly   215 SKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINE-------- 271
            ...||...|:||:|||.||:|:..|:|||.....|...|..:.|||..:.|..|.|:
 Worm   303 IDSYTNLADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKIENDNSSAIKAV 367

  Fly   272 -------KARNYLESLPFKPNVPWAKLF----PNADALALDLLGKMLTFNPHKRIPVEEALAHPY 325
                   |.||:.:            :|    |:.|  .:|||.|:|..:|.|||.||||:.|||
 Worm   368 IQSYTTHKRRNFRD------------VFSAHNPSED--FIDLLEKLLVLDPEKRITVEEAIQHPY 418

  Fly   326 LEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKFK 368
            |.::..|.|||.|:..|.:: ::...:|...:..:::|.:.:|
 Worm   419 LAEFSLPEDEPRADHIFDLD-DSQARTRFEWRDAVWKEIMNYK 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	137/364 (38%)
pmk-3	NP_001379550.1	STKc_p38	102..461	CDD:143356	138/368 (38%)