Protein Alignment rl and cdk-12

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001367220.1
• Gene: cdk-12 / 175559
• WormBaseID: WBGene00007135
• Length: 734
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 116/324 - (35%)
• Similarity: 176/324 - (54%)
• Gaps: 23/324 - (7%)

  Fly    38 YIKLAYIGEGAYGMVVSADDTLTNQRVAIKKIS-PFEHQTYCQRTLREITILTRFKHENIIDIRD 101
            |..|..||||.||.|..|.:.||.::||:|::. ..|.:.:....:|||.||.:..|:||:.:.|
 Worm   311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMD 375

  Fly   102 ILRVD-SIDQMR----DVYIVQCLMETDLYKLLKTQRL---SNDHICYFLYQILRGLKYIHSANV 158
            |:..| |:|:::    :.|:|...::.||..||:::.|   :.|.||....|:|.||.|||:...
 Worm   376 IVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGF 440

  Fly   159 LHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSID 223
            ||||:|.||:|:|...:|||.|.||||:.:.|   :...|..|.|.|||.||::|..:.|..:||
 Worm   441 LHRDIKCSNILVNNKGELKIADLGLARLWEKE---SRLYTNRVITLWYRPPELLLGDERYGPAID 502

  Fly   224 IWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRD---DLECIINEKARNYLESLPFKPN 285
            :||.||:|.|:.:.:|:|.|.:...||..|..|.|||:.|   :|..::.........:...:..
 Worm   503 VWSTGCMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIR 567

  Fly   286 VPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMEND 349
            ..:..:.|..   |:|||.||||.||.|||..:|||.||::...     |.....|.::....|
 Worm   568 EEFEHIMPRE---AVDLLDKMLTLNPEKRISAKEALNHPWIRSL-----EHTTVQPLKLPQHQD 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	116/324 (36%)
cdk-12	NP_001367220.1	STKc_CDK12	303..605	CDD:270847	113/299 (38%)