DRSC/TRiP Functional Genomics Resources

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Protein Alignment rl and mpk-2

DIOPT Version :9

Sequence 1:NP_001015122.1 Gene:rl / 3354888 FlyBaseID:FBgn0003256 Length:376 Species:Drosophila melanogaster
Sequence 2:NP_494946.2 Gene:mpk-2 / 173880 WormBaseID:WBGene00003402 Length:605 Species:Caenorhabditis elegans


Alignment Length:382 Identity:150/382 - (39%)
Similarity:224/382 - (58%) Gaps:15/382 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FNSSGSVVNGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKK 68
            ::.|.:.||.:......:|:|. :.|:.:..|..|:....:|.||||:|..|.||...::|||||
 Worm    24 YSISKNTVNKSKMAAPAESHAR-LDGRFWLEGTPYLAEENVGAGAYGVVCKAMDTRNKKQVAIKK 87

  Fly    69 I-SPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKT- 131
            | ..|...|..:|:|||:.||....|||||.:.|:...:.. ..:|:|:|..||||||:::|.: 
 Worm    88 IPRAFTAHTLAKRSLREVRILRELLHENIIAVLDMFTAEGA-HGKDIYLVMDLMETDLHQILHSR 151

  Fly   132 QRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARI---ADPEHDH 193
            |.|...|..||.||:||||||:|||.::||||||||||||..|.|:|.|||:||.   |....|.
 Worm   152 QTLMEQHFQYFFYQLLRGLKYLHSAGIIHRDLKPSNLLLNGDCLLRIADFGMARAYASASTVRDD 216

  Fly   194 T---GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG 255
            .   |.:|:||:|||||||||:.:...|...:|:||.|||.||||..|.:||||..:.|:..|:.
 Worm   217 ANVGGHMTQYVSTRWYRAPEILFSMVEYDTKVDLWSAGCIFAEMLLRRQLFPGKDSVSQIKMIVY 281

  Fly   256 VLGSPSRDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEA 320
            .||||..:.:..|.::..|:.:|:...|..:|::.:||.|...|.:::..:|..:|.||...::.
 Worm   282 YLGSPEEEVINRITSDLVRDSIEACGRKTPLPFSAIFPKASPEARNMVSYLLQISPWKRYSADQI 346

  Fly   321 LAHPYLEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIF---EETLKFKERQPDN 374
            |.||::.||::...||:.  |.|:.::.|.|.|.....::.   ||...|:.|:..|
 Worm   347 LQHPFMAQYHNDQYEPLC--PPRVQVDVDAIERFEGAQVVAGLDEEARIFEMRRGTN 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
rlNP_001015122.1 STKc_ERK1_2_like 32..366 CDD:270839 141/344 (41%)
S_TKc 38..326 CDD:214567 129/295 (44%)
mpk-2NP_494946.2 PKc_like 54..376 CDD:304357 137/324 (42%)
S_TKc 57..352 CDD:214567 129/295 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D309855at33208
OrthoFinder 1 1.000 - - FOG0000164
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100339
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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