Protein Alignment rl and kin-3

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_492811.1
• Gene: kin-3 / 172978
• WormBaseID: WBGene00002191
• Length: 360
• Species: Caenorhabditis elegans
• Alignment Length: 352
• Identity: 105/352 - (29%)
• Similarity: 180/352 - (51%)
• Gaps: 48/352 - (13%)

  Fly    11 VNGTGSTEVPQSNAEVIR-GQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEH 74
            ||.:...|.....|.:|. |||.:    |..:..:|.|.|..|.......|:::|.:|.:.|.:.
 Worm    14 VNPSRPREYWDYEAHMIEWGQIDD----YQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKK 74

  Fly    75 QTYCQRTLREITILTRFK-HENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDH 138
                ::..|||.||...: ..|||.:.|::: |.|.: ....|.:.:..:|..:|.:|  ||:..
 Worm    75 ----KKIKREIKILENLRGGTNIITLLDVVK-DPISR-TPALIFEHVNNSDFKQLYQT--LSDYD 131

  Fly   139 ICYFLYQILRGLKYIHSANVLHRDLKPSNLLLN-KTCDLKICDFGLARIADPEHDHTGFLTEYVA 202
            |.|:||::|:.|.:.||..::|||:||.|:::: :..:|::.|:|||....|..|:    ...||
 Worm   132 IRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDY----NVRVA 192

  Fly   203 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PIFPGKHYLDQLNHILGVLGSPSRDDLE 266
            :|:::.||::::.:.|..|:|:||:||:||.|:..: |.|.|....|||..|..|||:   |:|.
 Worm   193 SRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGT---DELY 254

  Fly   267 CIINEKARNYLESLPFKPNV-------PWAKLFPNAD------ALALDLLGKMLTFNPHKRIPVE 318
            ..|   ||.:::..|...::       .|.: |.:|:      ..|||.|.|:|.::..:|:..:
 Worm   255 EYI---ARYHIDLDPRFNDILGRHSRKRWER-FIHAENQHLVTPEALDFLDKLLRYDHAERLTAQ 315

  Fly   319 EALAHPYLEQYYDPGDEPVAEVPFRIN 345
            ||:.|.|.        .||.|...|.|
 Worm   316 EAMGHEYF--------RPVVEAHARAN 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	97/330 (29%)
kin-3	NP_492811.1	STKc_CK2_alpha	19..323	CDD:271034	97/326 (30%)