Protein Alignment rl and CSNK2A2

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001887.1
• Gene: CSNK2A2 / 1459
• HGNCID: 2459
• Length: 350
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 92/319 - (28%)
• Similarity: 163/319 - (51%)
• Gaps: 49/319 - (15%)

  Fly    44 IGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSI 108
            :|.|.|..|..|.:...|:||.:|.:.|.:.    ::..||:.||     ||:....:|:::  |
Human    46 LGRGKYSEVFEAINITNNERVVVKILKPVKK----KKIKREVKIL-----ENLRGGTNIIKL--I 99

  Fly   109 DQMRD------VYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSN 167
            |.::|      ..:.:.:..||..:|.  |.|::..|.:::|::|:.|.|.||..::|||:||.|
Human   100 DTVKDPVSKTPALVFEYINNTDFKQLY--QILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHN 162

  Fly   168 LLL-NKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCIL 231
            ::: ::...|::.|:|||....|..::    ...||:|:::.||::::.:.|..|:|:||:||:|
Human   163 VMIDHQQKKLRLIDWGLAEFYHPAQEY----NVRVASRYFKGPELLVDYQMYDYSLDMWSLGCML 223

  Fly   232 AEMLSNR-PIFPGKHYLDQLNHILGVLGS---------------PSRDDLECIINEKARNYLESL 280
            |.|:..| |.|.|:...|||..|..|||:               |..:|   |:.:.:|...|:.
Human   224 ASMIFRREPFFHGQDNYDQLVRIAKVLGTEELYGYLKKYHIDLDPHFND---ILGQHSRKRWENF 285

  Fly   281 PFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAE 339
            ....|.....  |.    |||||.|:|.::..:|:..:||:.|||.........:|.|:
Human   286 IHSENRHLVS--PE----ALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCAD 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	92/319 (29%)
CSNK2A2	NP_001887.1	STKc_CK2_alpha	22..326	CDD:271034	90/305 (30%)