Protein Alignment rl and CDK7

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001790.1
• Gene: CDK7 / 1022
• HGNCID: 1778
• Length: 346
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 124/322 - (38%)
• Similarity: 171/322 - (53%)
• Gaps: 41/322 - (12%)

  Fly    37 RYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQ----RT-LREITILTRFKHENI 96
            ||.||.::|||.:..|..|.|..|||.||||||. ..|::..:    || ||||.:|....|.||
Human    11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIK-LGHRSEAKDGINRTALREIKLLQELSHPNI 74

  Fly    97 IDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQR--LSNDHICYFLYQILRGLKYIHSANVL 159
            |.:     :|:.....::.:|...|||||..::|...  |:..||..::...|:||:|:|...:|
Human    75 IGL-----LDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWIL 134

  Fly   160 HRDLKPSNLLLNKTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSID 223
            ||||||:||||::...||:.|||||: ...|...:    |..|.||||||||::..::.|...:|
Human   135 HRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAY----THQVVTRWYRAPELLFGARMYGVGVD 195

  Fly   224 IWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRD---DLECIINEKARNYLESLP---- 281
            :|:|||||||:|...|..||...||||..|...||:|:.:   |: |           |||
Human   196 MWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM-C-----------SLPDYVT 248

  Fly   282 FK--PNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVP 341
            ||  |.:|...:|..|....|||:..:..|||..||...:||...|...  .||..|..::|
Human   249 FKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN--RPGPTPGCQLP 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	124/322 (39%)
CDK7	NP_001790.1	STKc_CDK7	11..308	CDD:270833	123/320 (38%)