DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rl and mapk6

DIOPT Version :9

Sequence 1:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_002936385.1	Gene:	mapk6 / 100494114	XenbaseID:	XB-GENE-478419	Length:	720	Species:	Xenopus tropicalis

Alignment Length:	331	Identity:	151/331 - (45%)
Similarity:	212/331 - (64%)	Gaps:	14/331 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRFKHENI 96
            |::|.||:.|..:|.|..|:|.||.|...::|||:|||...:.|: .:..||||.|:.|..|:||
Frog    14 FDLGSRYMDLKPLGYGGNGLVFSAVDNDCDKRVAVKKIVLTDPQS-VKHALREIKIIRRLDHDNI 77

  Fly    97 IDIRDIL---------RVDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKY 152
            :.:.:||         .|.|:.::..|||||..|||||.|||:...|..:|...|:||:||||||
Frog    78 VKVFEILGPNGRQLTDDVSSLTELNCVYIVQDYMETDLAKLLEQGPLREEHARLFMYQLLRGLKY 142

  Fly   153 IHSANVLHRDLKPSNLLLNKTCDL--KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNS 215
            |||||||||||||:||.:| |.||  ||.|||||||.||.:.|.|.|:|.:.|:|||:|.::|:.
Frog   143 IHSANVLHRDLKPANLFIN-TEDLVVKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSP 206

  Fly   216 KGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESL 280
            ..|||:||:|:.|||.||||:.:.:|.|.|.|:|:..||..:.....:|.:.::| ....|:::.
Frog   207 NNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQMQLILESIPVVHEEDRQELLN-VIPVYIKND 270

  Fly   281 PFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRIN 345
            ..:|:.|..:|.|...:.|||.|.::|||:|..|:..||||:|||:..|..|.|||::..||.|.
Frog   271 MSEPHKPLTQLLPGISSEALDFLEQILTFSPMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIE 335

  Fly   346 MENDDI 351
            .|.|||
Frog   336 DEVDDI 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	151/331 (46%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	135/298 (45%)
mapk6	XP_002936385.1	STKc_MAPK4_6	14..355	CDD:143359	151/331 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920