Protein Alignment rl and cdkl2

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_002938668.2
• Gene: cdkl2 / 100487310
• XenbaseID: XB-GENE-5959638
• Length: 565
• Species: Xenopus tropicalis
• Alignment Length: 359
• Identity: 108/359 - (30%)
• Similarity: 184/359 - (51%)
• Gaps: 52/359 - (14%)

  Fly    37 RYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQR-TLREITILTRFKHENIIDIR 100
            :|..|..:|||:||||:...:....:.||:||....|.....:: .:|||.:|.:.:|||::::.
 Frog     3 KYENLGLVGEGSYGMVMKCRNKENGRIVAVKKFLESEDDKMVKKIAMREIKLLKQLRHENLVNLL 67

  Fly   101 DILR----------------VDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRG 149
            ::.:                :|.::|..:        ..|..|:.|           :|:||:||
 Frog    68 EVCKKKKRWYLVFEFVDRTVLDDLEQFPN--------GLDFSKVRK-----------YLFQIIRG 113

  Fly   150 LKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIML 213
            :.:.||.|::|||:||.|:|::.:..:|:||||.|| :|.|..|:    |:|||||||||||:::
 Frog   114 IGFCHSHNIIHRDIKPENILVSHSGIVKLCDFGFARTLAGPGEDY----TDYVATRWYRAPELLV 174

  Fly   214 NSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLG--SPSRDDLECIINEKARNY 276
            ....|.|::|:|::|||:.|||:.:|:|||...:|||:||:...|  :|...:|.......|...
 Frog   175 GDIKYGKAVDVWAIGCIVTEMLTAQPLFPGDSDIDQLHHIVKCQGNLTPRHQELFYRNPMFAGFS 239

  Fly   277 LESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVP 341
            |..:....::.|.  :|....:.|||....|..:|.||......|.|....:  |...|..:: .
 Frog   240 LPDMKEAESLEWR--YPKLSPIMLDLAKSCLHIDPDKRPACMTLLLHELFTK--DSFSERFSQ-E 299

  Fly   342 FRINMENDDISRDALKSLIFEETLKFKERQPDNA 375
            .|..::|  :.:|  .||..::....|:.:.|.|
 Frog   300 IRAKLQN--LPKD--NSLQSKKLKNHKKEKEDYA 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	105/348 (30%)
cdkl2	XP_002938668.2	STKc_CDKL2_3	2..287	CDD:270836	98/308 (32%)