DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rl and XB956263

DIOPT Version :9

Sequence 1:	NP_001015122.1	Gene:	rl / 3354888	FlyBaseID:	FBgn0003256	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	XP_002938433.1	Gene:	XB956263 / 100145045	XenbaseID:	XB-GENE-956264	Length:	359	Species:	Xenopus tropicalis

Alignment Length:	346	Identity:	153/346 - (44%)
Similarity:	220/346 - (63%)	Gaps:	9/346 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKK-ISPFEHQTYCQRTLREITILTRFKHEN 95
            ::|..||..||.:|.||||.|.||.|.||.:|||||| :.||:...:.:|..||:.:|...||||
Frog    19 WDVPVRYRDLAAVGSGAYGTVCSAQDRLTGERVAIKKLLRPFQSLVHAKRAYRELRLLKHMKHEN 83

  Fly    96 IIDIRDILRVD-SIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVL 159
            :|.:.::...| |::..:..|:|...:..||.::::.|||::..|.|.||||||||:|||:|.::
Frog    84 VISLLNVFTPDESMETFQTFYLVMPFIAVDLSRVMRMQRLNHSTIVYLLYQILRGLQYIHAAGIV 148

  Fly   160 HRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDI 224
            |||||||||.:|:..:|||.||||||..:.|      :|.||.||||||||::||...|..::||
Frog   149 HRDLKPSNLGVNEDYELKILDFGLARPTEFE------MTGYVVTRWYRAPEVILNWMHYNHTVDI 207

  Fly   225 WSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPWA 289
            ||||||||||::.:.:|||..|.|:||.|:.|.|||....:..:.:..|::|::.||.|....:.
Frog   208 WSVGCILAEMITGKVLFPGGDYFDELNKIIEVTGSPQPSLINKMESSHAQDYVKMLPKKQKKNFK 272

  Fly   290 KLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISRD 354
            :|||...|:..|||.|||..:|..|:...|||||||||:|.|...:|.|: .:..:.|:.|::..
Frog   273 ELFPTMSAVETDLLEKMLDLDPGTRVNATEALAHPYLEEYNDSDPDPTAD-KYDDSFESLDLNVH 336

  Fly   355 ALKSLIFEETLKFKERQPDNA 375
            ..|||...|.:.|:..:|..|
Frog   337 EWKSLSHMEIMTFEPMKPSQA 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	150/335 (45%)
rl	NP_001015122.1	S_TKc	38..326	CDD:214567	135/289 (47%)
XB956263	XP_002938433.1	STKc_p38	9..351	CDD:143356	151/338 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910