Protein Alignment rl and nlk.2

DIOPT Version :10

• Sequence 1: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_031748355.1
• Gene: nlk.2 / 100144684
• XenbaseID: XB-GENE-1218923
• Length: 456
• Species: Xenopus tropicalis
• Alignment Length: 375
• Identity: 151/375 - (40%)
• Similarity: 211/375 - (56%)
• Gaps: 55/375 - (14%)

  Fly    20 PQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKI-SPFEHQTYCQRTLR 83
            ||.|.:. ||:.....|       ||.||:|:|.|..|....:|||:||: :.|::...|:|..|
 Frog    57 PQCNGDG-RGEPEPDRP-------IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFR 113

  Fly    84 EITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYK-LLKTQRLSNDHICYFLYQIL 147
            |:.:|..|||:|::...|||:...||...::|::..||:|||:| ::..|.||:|||..||||||
 Frog   114 ELKMLCFFKHDNVLSALDILQPPQIDCFEEIYVITELMQTDLHKVIVSPQPLSSDHIKVFLYQIL 178

  Fly   148 RGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIM 212
            |||||:|||.:||||:||.|||:|..|.||||||||||:  .|.|.:..:|:.|.|::||||||:
 Frog   179 RGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARV--EELDESQHMTQEVVTQYYRAPEIL 241

  Fly   213 LNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLE--CIINEKARN 275
            :.|:.|..:|||||||||.||:|..|.:|..:..:.||:.|..:||:|....:.  |   |.||.
 Frog   242 MGSRHYRSAIDIWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPPLTAMRSAC---EGARA 303

  Fly   276 YLESLPFKPNVPWAKLFPNADAL----------ALDLLGKMLTFNPHKRIPVEEALAHPYLEQ-- 328
            ::...|.||        |:...|          |:.||.:||.|:|.|||..::||||||||:
 Frog   304 HILRGPHKP--------PSLSVLYMLSGEATHEAVHLLCRMLLFDPLKRISAKDALAHPYLEEGR 360

  Fly   329 ------------------YYDPGDEPVAEVPFRINMENDDISRDALKSLI 360
                              .|....||.|...|..:.|....|...:|.|:
 Frog   361 LRYHTCMCHCCYSVSSGRVYTADFEPTATNRFDDSYEKSLTSVWQVKELV 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	146/363 (40%)
nlk.2	XP_031748355.1	STKc_NLK	66..437	CDD:173748	146/365 (40%)