DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klhl10 and AT1G55270

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_564684.1	Gene:	AT1G55270 / 841972	AraportID:	AT1G55270	Length:	434	Species:	Arabidopsis thaliana

Alignment Length:	359	Identity:	85/359 - (23%)
Similarity:	129/359 - (35%)	Gaps:	94/359 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 LNPQAD-------ELT--TPPLAMPRLPHEVIFAIGGWSGGTSKGCIETYDTRAD---------R 372
            :||.|.       |.|  .||| :|.||.::..|           |:... .||:         |
plant    57 INPNAHRRKNSKRERTRIQPPL-LPGLPDDLAVA-----------CLIRV-PRAEHRKLRLVCKR 108

  Fly   373 WVTINAEDPAGPRAYHGTAVLGFK-----IFSIGGYDGVEYFNTCRVFDAVKKKWNEIAPM---H 429
            |..:    .:|...|....:||..     :|. ...||...:||   ||.:.:.|..:.|:   :
plant   109 WYRL----ASGNFFYSQRKLLGMSEEWVYVFK-RDRDGKISWNT---FDPISQLWQPLPPVPREY 165

  Fly   430 CRRCYVSVTELNGM-IYAIGGYDG-HNRLNTVERYNPRTNQWSVIPPMNMQRSDASACTLQERIY 492
            ..........|:|. :|..||.|. ...:..|..||.|||:|...|.|..:|.....|.:...:|
plant   166 SEAVGFGCAVLSGCHLYLFGGKDPLRGSMRRVIFYNARTNKWHRAPDMLRKRHFFGCCVINNCLY 230

  Fly   493 ATGGFNGQEC------LDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQLYVIGGFNGTARLS 551
            ..||    ||      |.|||.|||..|.|:.|.:|:.....:..|.:..:.::.|  .|:.:|.
plant   231 VAGG----ECEGIQRTLRSAEVYDPNKNRWSFIADMSTAMVPLIGVVYDKKWFLKG--LGSHQLV 289

  Fly   552 TGERFDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTISHTECYVAE---------- 606
            ..|.:||:..:|.              .:.|.|   :.|:....|..:...|..:
plant   290 MSEAYDPEVNSWS--------------PVSDGM---VAGWRNPCTSLNGRLYGLDCRDGCKLRVF 337

  Fly   607 ---TDEWMEATDMNI---VRSALSANNIAGLPNK 634
               ||.|.:..|...   ...:|.|..:..|.||
plant   338 DESTDSWNKFMDSKAHLGNSKSLEAAALVPLHNK 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045
		PHA03098	86..610	CDD:222983	78/330 (24%)
		BACK	195..298	CDD:285009
		Kelch	347..394	CDD:128874	8/55 (15%)
		KELCH repeat	385..428	CDD:276965	11/47 (23%)
		Kelch	396..442	CDD:128874	10/53 (19%)
		Kelch_1	431..476	CDD:279660	14/46 (30%)
		KELCH repeat	432..475	CDD:276965	14/44 (32%)
		KELCH repeat	479..523	CDD:276965	17/49 (35%)
		Kelch	490..536	CDD:128874	17/51 (33%)
		Kelch_1	525..570	CDD:279660	8/44 (18%)
		KELCH repeat	526..571	CDD:276965	8/44 (18%)
		Kelch_1	573..617	CDD:279660	9/56 (16%)
		KELCH repeat	573..617	CDD:276965	9/56 (16%)
AT1G55270	NP_564684.1	F-box	77..119	CDD:395521	12/58 (21%)
		KELCH repeat	170..213	CDD:276965	14/42 (33%)
		PHA03098	<171..356	CDD:222983	50/207 (24%)
		KELCH repeat	217..263	CDD:276965	17/49 (35%)
		KELCH repeat	266..306	CDD:276965	8/55 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860