DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klhl10 and AT4G39760

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_195686.1	Gene:	AT4G39760 / 830134	AraportID:	AT4G39760	Length:	369	Species:	Arabidopsis thaliana

Alignment Length:	390	Identity:	75/390 - (19%)
Similarity:	131/390 - (33%)	Gaps:	119/390 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   328 PQADELTTPPLAMPRLPHEVIFAIGGWSGGT--SKGCI------------ETYDTRADR------ 372
            ||:   |...|:...||||::.:......|:  .|.|:            |.|..|:..
plant     8 PQS---TNHSLSFSSLPHEIVVSCLARVSGSYYPKLCLVSKQFRSIILSNEIYKARSHLGTKENR 69

  Fly   373 ---WVTINAEDPAGPRAYHGTAVLGFKIFSIGGYDGVEYFNTCRVFDAVKKK--WNEIAPMHCRR 432
               |:.:..      |:|.....|..|.......||           .:||:  .|.:.|:.|..
plant    70 LFVWLKLPT------RSYPSWFALWIKPNETLTNDG-----------PIKKQSTGNLLVPLPCSY 117

  Fly   433 CY---VSVTELNGMIYAIGGYDGHNRLNTVERYNPRTNQWSVIPPMNMQRSDASACTLQERIYAT 494
            .|   |....:....|.:||||.....:.....|.:.:..|..|.|::.|.||........||..
plant   118 NYQVLVPSVIVGSETYIVGGYDDALSSSVWFYKNGKIHTLSKSPSMSVARIDAVVVGQYPNIYVM 182

  Fly   495 GGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQ---LYVIGGFNGTARLSTGER- 555
            ||.:..|.::..|.::..|..|..:|:......|......:.|   :||           :.|:
plant   183 GGCDSDESMNWGEVFNIKTQTWEPLPDPGPEVRGQLVRKMKMQKKNVYV-----------SSEKK 236

  Fly   556 ---FDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTISHTECYVAET--DEWMEATD 615
               :|.:.:||    ::..:..||...:|:.:.:.....|         |:..:|  .:|
plant   237 DYIYDTEERTW----KVTEAVFNFSWCVIEKVRYIYYNKN---------CWWLDTKSKDW----- 283

  Fly   616 MNIVRSALSANNIAGLPNKRDYIHK--ERDRL-----------------MEERRQRLMATAMARE 661
                      ..|.||    |:::|  |.||:                 :.:|.:::....:|.|
plant   284 ----------RKIKGL----DFLNKFRETDRIEIVNLDGKLVMIWDRFTLSKRNKKIWCAMIALE 334

Fly 662 661
plant 335 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045
		PHA03098	86..610	CDD:222983	63/318 (20%)
		BACK	195..298	CDD:285009
		Kelch	347..394	CDD:128874	9/69 (13%)
		KELCH repeat	385..428	CDD:276965	9/44 (20%)
		Kelch	396..442	CDD:128874	10/50 (20%)
		Kelch_1	431..476	CDD:279660	10/47 (21%)
		KELCH repeat	432..475	CDD:276965	10/45 (22%)
		KELCH repeat	479..523	CDD:276965	12/43 (28%)
		Kelch	490..536	CDD:128874	10/45 (22%)
		Kelch_1	525..570	CDD:279660	8/51 (16%)
		KELCH repeat	526..571	CDD:276965	8/51 (16%)
		Kelch_1	573..617	CDD:279660	7/45 (16%)
		KELCH repeat	573..617	CDD:276965	7/45 (16%)
AT4G39760	NP_195686.1	F-box	16..62	CDD:279040	10/45 (22%)
		KELCH repeat	167..212	CDD:276965	12/44 (27%)
		Kelch_1	170..211	CDD:279660	10/40 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810