DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klhl10 and AT4G39240

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_195635.1	Gene:	AT4G39240 / 830080	AraportID:	AT4G39240	Length:	375	Species:	Arabidopsis thaliana

Alignment Length:	400	Identity:	78/400 - (19%)
Similarity:	142/400 - (35%)	Gaps:	133/400 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 VKWIDRNPESRKRHVAHLMTGVRLGLMTPKC------FMEEVKEHPYVLECEAAKP--------L 312
            |..|...|..:|:|..           :|.|      ..:|:     :|.|.|..|        |
plant    11 VSSIAEEPPPKKQHDP-----------SPSCSSYLLLLPDEI-----ILNCLARLPKCYYPVISL 59

  Fly   313 IVDTFKFMYDLDFLNPQADELTTPPL----AMPRLPHEVIFAIGGWSGGTSKGCIETYDTRADRW 373
            :..||:.:            :.:|.:    ::.|....|::.:           :.::.|...||
plant    60 VSKTFRRL------------IASPEIYVERSLLRRTERVLYVV-----------LRSHATETPRW 101

  Fly   374 VTINAEDPAGPRAYH--------------GTAVLGF--KIFSIGGYDGVEYF----------NTC 412
            .|:|.:........|              |.:::..  :|:.:||....|..          :||
plant   102 YTLNFKPFGNDSNNHRLVPIPSFPSIPCWGMSIVAIDSEIYVLGGCIDNELVSTGFVVECPSHTC 166

  Fly   413 RVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYDGHNRLNTVERYNPRTNQW-SVIPPMN 476
            |:..::|:         .|.| .:|...:|.:|.|||.:..: :|.||.::.:|..| |.:...|
plant   167 RLLPSMKQ---------ARGC-AAVGFFDGKLYVIGGCNPLS-VNWVEAFDLKTQTWESGLGVNN 220

  Fly   477 MQRSDAS--ACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQLY 539
            ::..|.:  :..:.::||.....|       :..|||..........::.:.|..||| ...::|
plant   221 VEMHDLTIRSFAIDDKIYIMDRKN-------SFVYDPKEGTLETDELLDTQWSVGSCV-IDGKIY 277

  Fly   540 VIGGFNGTARLSTGERFDPDTQTWHFIREMNHSRSNFGLEIIDD-----MIFAIGG-----FN-- 592
            ..|..|   |:..   |||....|..::         ||:.:.|     .:..:||     ||
plant   278 TFGSKN---RIWV---FDPIAMVWDRLK---------GLDDLPDKRDGSRMSNLGGNLAIMFNLE 327

  Fly   593 -GVSTISHTE 601
             |.:.|..||
plant   328 KGSTKICCTE 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045
		PHA03098	86..610	CDD:222983	77/399 (19%)
		BACK	195..298	CDD:285009	8/41 (20%)
		Kelch	347..394	CDD:128874	8/60 (13%)
		KELCH repeat	385..428	CDD:276965	10/68 (15%)
		Kelch	396..442	CDD:128874	11/55 (20%)
		Kelch_1	431..476	CDD:279660	14/45 (31%)
		KELCH repeat	432..475	CDD:276965	13/43 (30%)
		KELCH repeat	479..523	CDD:276965	7/45 (16%)
		Kelch	490..536	CDD:128874	10/45 (22%)
		Kelch_1	525..570	CDD:279660	12/44 (27%)
		KELCH repeat	526..571	CDD:276965	12/44 (27%)
		Kelch_1	573..617	CDD:279660	10/41 (24%)
		KELCH repeat	573..617	CDD:276965	10/41 (24%)
AT4G39240	NP_195635.1	F-box	34..79	CDD:279040	9/61 (15%)
		Kelch_1	131..173	CDD:279660	8/41 (20%)
		KELCH repeat	131..172	CDD:276965	8/40 (20%)
		Kelch_1	175..215	CDD:279660	13/41 (32%)
		KELCH repeat	176..224	CDD:276965	15/49 (31%)
		KELCH repeat	264..298	CDD:276965	12/40 (30%)
		Kelch_2	269..301	CDD:284956	11/47 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810