DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klhl10 and AT4G33900

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_567939.1	Gene:	AT4G33900 / 829533	AraportID:	AT4G33900	Length:	379	Species:	Arabidopsis thaliana

Alignment Length:	427	Identity:	81/427 - (18%)
Similarity:	136/427 - (31%)	Gaps:	165/427 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 RFRFLED---LHLKARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTREEDHVWKLCVKW 264
            ||..|.|   .:..||...|.|.|         |.:.::.|..:::..||
plant    11 RFLMLPDDLVFNCLARVSRLHYPT---------LSLVSKKFRFLLASKEL--------------- 51

  Fly   265 IDRNPESRKRHVAHLMTGVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLDFLNPQ 329
                          ..|.:.|| .|..|....|:.|             .|:.:..:.:.:..|.
plant    52 --------------YQTRILLG-GTESCLYVCVRLH-------------TDSEQLHWFIIYQGPN 88

  Fly   330 ADELTTPPLAMPR-----LP------HEVIFAIGGWSGGTSKGCIETYDTRADRWVTINAEDPAG 383
            :.:....|::.|.     ||      || |:||||  |..:|.            .:|||   .|
plant    89 SSKKVLVPISSPNFTSAALPGFVVVGHE-IYAIGG--GSENKN------------ASINA---TG 135

  Fly   384 PRAYHGTAVLGFKIFSIGGYDGVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIG 448
            .:.|:.                   .::..|.|:....|.|...|...|.:.|...|:|.||..|
plant   136 SKTYNA-------------------LSSVMVMDSRSHTWREAPSMRVARVFPSACTLDGRIYVTG 181

  Fly   449 GYDGHNRLNTVERYNPRTNQWSV--IPPMNM-QRSDASACTLQERIYA------------TGGFN 498
            |.:..|.:|.:|.::.:|..|..  ||...: :.|:..:.:.|..:|.            .|.:.
plant   182 GCENLNSMNWMEIFDTKTQTWEFLQIPSEEVCKGSEYLSISYQRTVYVGSREKDVTYKMHKGKWR 246

  Fly   499 GQE-CLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQLYVIGGFNGTARLSTGERFDPDTQT 562
            |.: ||:..         |:..|:        ||....|..|         |.|.|:      ..
plant   247 GADICLNHG---------WSLDPS--------SCCVIENVFY---------RCSLGD------VR 279

  Fly   563 WHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTISH 599
            |:.:::...:              |:.|..|:.|.::
plant   280 WYDLKKREWA--------------ALKGLEGLPTFTN 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045
		PHA03098	86..610	CDD:222983	81/427 (19%)
		BACK	195..298	CDD:285009	18/97 (19%)
		Kelch	347..394	CDD:128874	12/46 (26%)
		KELCH repeat	385..428	CDD:276965	5/42 (12%)
		Kelch	396..442	CDD:128874	8/45 (18%)
		Kelch_1	431..476	CDD:279660	15/46 (33%)
		KELCH repeat	432..475	CDD:276965	15/44 (34%)
		KELCH repeat	479..523	CDD:276965	9/56 (16%)
		Kelch	490..536	CDD:128874	9/58 (16%)
		Kelch_1	525..570	CDD:279660	8/44 (18%)
		KELCH repeat	526..571	CDD:276965	8/44 (18%)
		Kelch_1	573..617	CDD:279660	4/27 (15%)
		KELCH repeat	573..617	CDD:276965	4/27 (15%)
AT4G33900	NP_567939.1	F-box	11..54	CDD:395521	13/80 (16%)
		PHA03098	<88..288	CDD:222983	55/268 (21%)
		KELCH repeat	109..162	CDD:276965	18/89 (20%)
		Kelch_1	164..205	CDD:396078	13/40 (33%)
		KELCH repeat	165..205	CDD:276965	13/39 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810