DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klhl10 and AT3G10510

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_187662.1	Gene:	AT3G10510 / 820215	AraportID:	AT3G10510	Length:	371	Species:	Arabidopsis thaliana

Alignment Length:	326	Identity:	60/326 - (18%)
Similarity:	107/326 - (32%)	Gaps:	128/326 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 KCKDYLGRILTPENCVSIMGFARFRFLEDLHLK-ARNYTLRYFTEVAYRNI------------DI 232
            |.:..||   ..|:||.::       :||..|: ||.|:|...|:   ||:            .:
plant    57 KTRSLLG---CTEDCVYVL-------IEDCILEVARWYSLNRRTK---RNMPGTVENRLVLISSL 108

  Fly   233 LDMSAEDFYSIISDD--------ELNTREEDHVWK--------LCVKWIDRNPESRKRHVAHLMT 281
            ..|.....|.::..:        :.|..|    |:        ||:        ..:.|...|:.
plant   109 PPMPTAASYVVVGSNIFVMGGRYDWNVEE----WEAQPPSSIALCI--------DCRTHTTRLVA 161

  Fly   282 GVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLDFLNPQADELTTPPLAMPRLPHE 346
            .:.:||||.  ..:.:.|..|::....|...||:     :||     :.::
plant   162 DMPVGLMTN--VSKVIDEKIYIVGRVWASATIVE-----FDL-----RTEK-------------- 200

  Fly   347 VIFAIGGWSGGTSKGCIETYDTRADRWVT-INAEDPAGPRAYHGTAVLGFKIFSIGGYDGVEYFN 410
                   |:.||..|.     ...|||:| ::.....||.::.                     |
plant   201 -------WADGTKPGW-----EADDRWLTSLSTTAGRGPSSFE---------------------N 232

  Fly   411 TC--RVFDAVKKKWNEIAPMHC--RRCYVSVTELNGMIYAIGGYDGHNRLNTVERYNPRTNQWSV 471
            .|  ::.:.:.....||...|.  ..|.     :..::|.   ||.|..:  :..|:|:...|.|
plant   233 NCDHKLMEDILMDKEEIKHYHLFDNECV-----MGNILYV---YDRHKYI--LRTYDPKQRTWGV 287

  Fly   472 I 472
            :
plant   288 V 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045	1/4 (25%)
		PHA03098	86..610	CDD:222983	60/326 (18%)
		BACK	195..298	CDD:285009	25/131 (19%)
		Kelch	347..394	CDD:128874	10/47 (21%)
		KELCH repeat	385..428	CDD:276965	4/44 (9%)
		Kelch	396..442	CDD:128874	6/49 (12%)
		Kelch_1	431..476	CDD:279660	9/42 (21%)
		KELCH repeat	432..475	CDD:276965	9/41 (22%)
		KELCH repeat	479..523	CDD:276965
		Kelch	490..536	CDD:128874
		Kelch_1	525..570	CDD:279660
		KELCH repeat	526..571	CDD:276965
		Kelch_1	573..617	CDD:279660
		KELCH repeat	573..617	CDD:276965
AT3G10510	NP_187662.1	F-box	15..61	CDD:279040	1/3 (33%)
AT3G10510	NP_187662.1	KELCH repeat	115..164	CDD:276965	8/60 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810