DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment klhl10 and AT2G44700

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_181998.1	Gene:	AT2G44700 / 819078	AraportID:	AT2G44700	Length:	368	Species:	Arabidopsis thaliana

Alignment Length:	269	Identity:	56/269 - (20%)
Similarity:	87/269 - (32%)	Gaps:	85/269 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 ETYDTRADRWVTINAED---------------PAGPRAYHGTAVLGFKIFSIGGYDGVEYFNTC- 412
            |.|....|.|.|:...:               |:.|..:...|| |.|||.|.        .:|
plant    86 ENYRPVYDYWYTLRRIENSTTENLFESIEFPYPSEPNRFSMNAV-GPKIFFIS--------ESCT 141

  Fly   413 -----RVFDAVKKKWNEIAPMHC---RRCYVSVTELNGMIYAIGGYDGHNRLNTVERYNPRTNQW 469
                 .:||.   ::.|:....|   :|.|..|..:.|.:|.||||....  ...|.::..|..|
plant   142 PSSRLSIFDT---RFGELRQGPCLLVKRGYNCVGLVGGKVYVIGGYQDDE--IAAESFDLNTQTW 201

  Fly   470 SVIPPMNMQRS-----------DASACTLQERIYATGGFNGQECLD----SAEYYDPVTNVWTRI 519
            ...|..:.:.|           |...|.|:.|       .|..|.|    |.:..:...:.|:|:
plant   202 EAAPIPDEKESHRWICKANVSFDRKVCALRSR-------EGMTCYDTRDGSCQRSEMPNDQWSRV 259

  Fly   520 PNMNHRRSGVSCVAFRNQLYVIGGFNGTARLSTGERFDPDTQTWHFIREMNHSRSNFGLEIIDDM 584
                    |: || ..|.|:|.....|..      .:|.....|..:         :|.::.:..
plant   260 --------GL-CV-IDNVLFVYFSRFGLM------WYDSKLMLWRVV---------YGFDLDNAR 299

  Fly   585 IFAIGGFNG 593
            ...||.:.|
plant   300 SVGIGEYYG 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045
		PHA03098	86..610	CDD:222983	56/269 (21%)
		BACK	195..298	CDD:285009
		Kelch	347..394	CDD:128874	9/44 (20%)
		KELCH repeat	385..428	CDD:276965	11/48 (23%)
		Kelch	396..442	CDD:128874	12/54 (22%)
		Kelch_1	431..476	CDD:279660	13/44 (30%)
		KELCH repeat	432..475	CDD:276965	13/42 (31%)
		KELCH repeat	479..523	CDD:276965	11/58 (19%)
		Kelch	490..536	CDD:128874	10/49 (20%)
		Kelch_1	525..570	CDD:279660	9/44 (20%)
		KELCH repeat	526..571	CDD:276965	9/44 (20%)
		Kelch_1	573..617	CDD:279660	4/21 (19%)
		KELCH repeat	573..617	CDD:276965	4/21 (19%)
AT2G44700	NP_181998.1	F-box	28..73	CDD:279040
		KELCH repeat	123..162	CDD:276965	11/50 (22%)
		KELCH repeat	166..207	CDD:276965	13/42 (31%)
		Kelch_1	166..205	CDD:279660	12/40 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810