DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klhl10 and SKIP6

DIOPT Version :9

Sequence 1:	NP_001015100.2	Gene:	klhl10 / 3354863	FlyBaseID:	FBgn0040038	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_565522.1	Gene:	SKIP6 / 816731	AraportID:	AT2G21950	Length:	372	Species:	Arabidopsis thaliana

Alignment Length:	354	Identity:	77/354 - (21%)
Similarity:	120/354 - (33%)	Gaps:	122/354 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 DRNPESRK--RHVAHLMTGVRLGLM--TPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLDFL 326
            |..||::.  :.:..|...|.|..:  .|:|       |..:|.      |:..||:
plant     9 DEPPETKSPAQLIPLLSEDVALSCLARVPRC-------HYPILS------LVSKTFR-------- 52

  Fly   327 NPQADELTTPPLAMPRLPHEVIFAIGGWSGGT-------------SKGCIETYDTRADRWVTI-- 376
                 .|.|.||         ::|.....|.|             |..|          |.|:
plant    53 -----SLPTSPL---------LYATRALVGATENILYVAIRIPPESGAC----------WFTLLH 93

  Fly   377 ----NAED-------PAGP------RAYHGTAVLGFKIFSIGGYDGVEYFNTCRVFDAVKKKWNE 424
                |:.:       |:.|      .||   .|:..:|:.|||.......::..|.|.....|..
plant    94 RTLSNSTNSKMLVPIPSCPSPSLVGSAY---VVVDSEIYVIGGSIRDVPSSSVWVLDCRFHTWRR 155

  Fly   425 IAPMHCRRCYVSVTELNGMIYAIGG--YDGHNR-LNTVERYNPRTNQWSVI--PPMNMQRSDASA 484
            ::.|...|.:.:...::|.||.|||  .|...| :|..|.::.:|..|..:  |.|.::.....|
plant   156 VSNMRVGREFAAAGVIDGKIYVIGGCVVDNWARSINWAEMFDIKTQTWEPVASPGMEVREKWMHA 220

  Fly   485 CTLQE-RIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRR-----SGVSCVAFRNQLY---V 540
            ..:.| ::||....||       ..|:|....|    .|..:|     .|.:|| ..|.||   .
plant   221 SAVMEGKVYAMADRNG-------VVYEPKEKKW----EMPEKRLDLGWRGRACV-IENILYCYDY 273

  Fly   541 IGGFNGTARLSTGERFDPDTQTWHFIREM 569
            :|...|         :||..:.|   ||:
plant   274 LGKIRG---------YDPKERIW---REL 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045
		PHA03098	86..610	CDD:222983	77/354 (22%)
		BACK	195..298	CDD:285009	8/35 (23%)
		Kelch	347..394	CDD:128874	13/78 (17%)
		KELCH repeat	385..428	CDD:276965	10/42 (24%)
		Kelch	396..442	CDD:128874	9/45 (20%)
		Kelch_1	431..476	CDD:279660	14/49 (29%)
		KELCH repeat	432..475	CDD:276965	14/47 (30%)
		KELCH repeat	479..523	CDD:276965	9/44 (20%)
		Kelch	490..536	CDD:128874	12/50 (24%)
		Kelch_1	525..570	CDD:279660	14/53 (26%)
		KELCH repeat	526..571	CDD:276965	14/52 (27%)
		Kelch_1	573..617	CDD:279660
		KELCH repeat	573..617	CDD:276965
SKIP6	NP_565522.1	F-box	21..64	CDD:279040	15/77 (19%)
		Kelch_1	117..160	CDD:279660	10/45 (22%)
		KELCH repeat	122..159	CDD:276965	8/36 (22%)
		muta_rot_YjhT	153..>352	CDD:274641	41/162 (25%)
		KELCH repeat	163..212	CDD:276965	14/48 (29%)
		Kelch_1	163..210	CDD:279660	13/46 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860