DRSC/TRiP Functional Genomics Resources

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Protein Alignment klhl10 and klhdc8a

DIOPT Version :9

Sequence 1:NP_001015100.2 Gene:klhl10 / 3354863 FlyBaseID:FBgn0040038 Length:767 Species:Drosophila melanogaster
Sequence 2:XP_001334194.3 Gene:klhdc8a / 794258 ZFINID:ZDB-GENE-120810-3 Length:354 Species:Danio rerio


Alignment Length:358 Identity:84/358 - (23%)
Similarity:141/358 - (39%) Gaps:86/358 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   328 PQADEL---TTPPLAMPRLPHEV------IFAIGGW-SGGTSKGCIETYDTRADRWVTINAEDPA 382
            |.|.|.   :...|:..|:.|.:      ::.:||. :.|.....:|.|....|||:::  ....
Zfish     4 PSAHEFHWQSLASLSSARVYHSLADVGGQLYLVGGCDASGQPTSALELYSPEVDRWLSL--PPMP 66

  Fly   383 GPRAYHGTAVLGFKIFSIGG-------YDGVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTEL 440
            .|||....||||.::..:||       ...||.:||      .:.||.:...:......||||..
Zfish    67 TPRAGAAVAVLGKQLLVVGGMGKEQRPLKAVEVYNT------DEGKWRKRCSLREASMGVSVTVK 125

  Fly   441 NGMIYAIGGYDGHNRL--NTVERYNPRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECL 503
            :|...|:||. |.:.|  :.:::|:.|.:.|:::|.|...|.|.|.|.|..:||..||...:..:
Zfish   126 DGRALAVGGM-GPDLLPRSVLQQYDLRKDVWALLPAMPTPRYDTSICLLGSKIYVAGGRQCKRLV 189

  Fly   504 DSAEYYDPVTNVWTRIPNMNHRR--SGV-----SCVAF--------------------------- 534
            .:.|.:|.....|:.:|::..:|  |||     .|:.:                           
Zfish   190 KAFEVFDMENRTWSSLPSLPCKRSYSGVLWDSAGCLCWLGGLRQGGIHQSSKFTKNVNIFDTNKG 254

  Fly   535 -----------------------RNQLYVIGGF-NGTARLSTGERFDPDTQTWHFIREMNHSRSN 575
                                   |.::.|.||. :..:.|.|.|.|.|:.:.|..:..|...|.:
Zfish   255 VWLKSEDTVPLKTKRADFAAAIVRGRMIVAGGLGHQPSVLDTVEAFHPEKRKWERLSPMATPRCS 319

  Fly   576 FGLEIIDDMIFAIGGFNGVSTISHTECYVAETD 608
            ....:|.|.:..:||.|.|.:.:|...||.|.:
Zfish   320 ASSIVIRDRLLVVGGVNQVPSSAHEILYVKEEE 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klhl10NP_001015100.2 BTB 72..186 CDD:279045
PHA03098 86..610 CDD:222983 84/358 (23%)
BACK 195..298 CDD:285009
Kelch 347..394 CDD:128874 13/53 (25%)
KELCH repeat 385..428 CDD:276965 14/49 (29%)
Kelch 396..442 CDD:128874 12/52 (23%)
Kelch_1 431..476 CDD:279660 14/46 (30%)
KELCH repeat 432..475 CDD:276965 14/44 (32%)
KELCH repeat 479..523 CDD:276965 13/43 (30%)
Kelch 490..536 CDD:128874 13/102 (13%)
Kelch_1 525..570 CDD:279660 15/102 (15%)
KELCH repeat 526..571 CDD:276965 16/102 (16%)
Kelch_1 573..617 CDD:279660 11/36 (31%)
KELCH repeat 573..617 CDD:276965 11/36 (31%)
klhdc8aXP_001334194.3 KELCH repeat 21..65 CDD:276965 10/45 (22%)
Kelch 32..79 CDD:128874 14/48 (29%)
Kelch_1 68..109 CDD:279660 15/46 (33%)
KELCH repeat 69..162 CDD:276965 28/99 (28%)
mutarot_permut 70..334 CDD:274642 60/270 (22%)
KELCH repeat 119..157 CDD:276965 13/38 (34%)
Kelch 131..171 CDD:128874 13/40 (33%)
KELCH repeat 165..209 CDD:276965 13/43 (30%)
Kelch 176..217 CDD:128874 10/40 (25%)
KELCH repeat 269..315 CDD:276965 11/45 (24%)
Kelch_1 269..313 CDD:279660 10/43 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.900

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