DRSC/TRiP Functional Genomics Resources

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Protein Alignment klhl10 and klhdc8a

DIOPT Version :9

Sequence 1:NP_001015100.2 Gene:klhl10 / 3354863 FlyBaseID:FBgn0040038 Length:767 Species:Drosophila melanogaster
Sequence 2:NP_001072317.1 Gene:klhdc8a / 779770 XenbaseID:XB-GENE-492242 Length:350 Species:Xenopus tropicalis


Alignment Length:316 Identity:78/316 - (24%)
Similarity:133/316 - (42%) Gaps:31/316 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   334 TTPPLAMPRLPHEV------IFAIGGW-SGGTSKGCIETYDTRADRWVTINAEDPAGPRAYHGTA 391
            |..||..||:...:      |||:||. ..|......|.:...|:||.::   :|. |.:..|.|
 Frog    13 TLAPLQSPRVYCSLVETGGQIFAVGGCDDAGNPMNSFEVFSPEANRWSSL---EPM-PSSRAGVA 73

  Fly   392 V--LGFKIFSIGGY-DGVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYDGH 453
            |  ||.:|..:||. :.........|::..:.||.:.:.:......:|||..:..:||.||....
 Frog    74 VVALGKRIMVVGGVGENQTPLKVVEVYNIDEGKWKKKSSLREPAMGISVTVRDCRVYAAGGMGSD 138

  Fly   454 NRLNT-VERYNPRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWT 517
            .|.:. :::|:...:.|....||...|..|::.....:||..||...:..:::.|.:|..|..||
 Frog   139 LRPHCFLQQYDMLKDIWVHFAPMPTPRYGATSFLRGTKIYVLGGRQAKYAVNAFEVFDIETRSWT 203

  Fly   518 RIPNMNHRRSGVSCVAFRNQLYVIGGF--NGTAR----LSTGERFDPDTQTWH------FIREMN 570
            :.|::.::|:....|.....||.:||.  .||.|    ..|.:.||.:...|.      |:|:  
 Frog   204 KFPSIPNKRAYSRYVLSEGSLYSLGGLRQGGTYRRPKFTKTVDIFDMEQGGWMKTERSCFLRK-- 266

  Fly   571 HSRSNFGLEIIDDMIFAIGGF-NGVSTISHTECYVAETDEWMEATDMNIVRSALSA 625
             .|::|....:...:...||. |..|.:...|.:......|...:.|...|.|.::
 Frog   267 -RRADFVAGSVHGRVVVAGGLGNQPSVLETAEIFHPVKSRWESLSPMPTPRCACAS 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klhl10NP_001015100.2 BTB 72..186 CDD:279045
PHA03098 86..610 CDD:222983 74/299 (25%)
BACK 195..298 CDD:285009
Kelch 347..394 CDD:128874 15/55 (27%)
KELCH repeat 385..428 CDD:276965 11/45 (24%)
Kelch 396..442 CDD:128874 9/46 (20%)
Kelch_1 431..476 CDD:279660 11/45 (24%)
KELCH repeat 432..475 CDD:276965 10/43 (23%)
KELCH repeat 479..523 CDD:276965 12/43 (28%)
Kelch 490..536 CDD:128874 12/45 (27%)
Kelch_1 525..570 CDD:279660 15/56 (27%)
KELCH repeat 526..571 CDD:276965 15/56 (27%)
Kelch_1 573..617 CDD:279660 8/44 (18%)
KELCH repeat 573..617 CDD:276965 8/44 (18%)
klhdc8aNP_001072317.1 PHA03098 <11..210 CDD:222983 52/200 (26%)
KELCH repeat 21..65 CDD:276965 11/46 (24%)
KELCH repeat 69..114 CDD:276965 11/44 (25%)
KELCH repeat 117..163 CDD:276965 12/45 (27%)
PHA03098 <145..349 CDD:222983 42/180 (23%)
KELCH repeat 165..209 CDD:276965 12/43 (28%)
KELCH repeat 268..313 CDD:276965 8/44 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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