DRSC/TRiP Functional Genomics Resources

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Protein Alignment klhl10 and Kbtbd13

DIOPT Version :9

Sequence 1:NP_001015100.2 Gene:klhl10 / 3354863 FlyBaseID:FBgn0040038 Length:767 Species:Drosophila melanogaster
Sequence 2:NP_083250.1 Gene:Kbtbd13 / 74492 MGIID:1921742 Length:458 Species:Mus musculus


Alignment Length:259 Identity:59/259 - (22%)
Similarity:104/259 - (40%) Gaps:37/259 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   416 DAVKKKWNEIA--PMHCRRCYVSVTELNGMIYAIGGYDGHNRLNTVER---YNPRTNQWSVIPPM 475
            |..:..|..:|  |:........|..|...:|.:||..|.:: ..||.   |:|....|...|..
Mouse   181 DEEEDAWRTLAALPLEASTLLAGVATLGNKLYIVGGVCGASK-EVVELGFCYDPEGGTWCEFPSP 244

  Fly   476 NMQRSDASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQLYV 540
            :..|.|.:....:.|:||.||...:..:.|.|.|||.|..|:.:.::....:||.|...|.:|:|
Mouse   245 HQPRYDMALAGFEGRLYAIGGEFQRTPMSSVECYDPATGCWSFVADLPQPATGVPCAQARGRLFV 309

  Fly   541 IGGFNGTARLSTGERFDPDTQTWHFIREMNHSRSNFGLEII--DDMIFAIGGFNGVS-TISH--T 600
            .  ....|.::....:......|..:.|:..|:| :|..::  .|.::.:.  ||.| ...|  .
Mouse   310 C--LWRPADITAVVEYVVQMDKWLPVAELCRSQS-YGHFMVAHRDSLYVVR--NGPSDDFLHCAI 369

  Fly   601 ECYVAETDEWME----------ATDMNIVR--SALSANNIAGLPNKRDYIHKERD---RLMEER 649
            :|....|.:|..          |...::||  :..:.|.::.|      ::...|   ||:.|:
Mouse   370 DCLNLVTGQWTSLPGQFVNSKGALFTSVVRGDTVYTVNRVSTL------VYAIEDGTWRLLREK 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klhl10NP_001015100.2 BTB 72..186 CDD:279045
PHA03098 86..610 CDD:222983 49/203 (24%)
BACK 195..298 CDD:285009
Kelch 347..394 CDD:128874
KELCH repeat 385..428 CDD:276965 3/13 (23%)
Kelch 396..442 CDD:128874 6/27 (22%)
Kelch_1 431..476 CDD:279660 12/47 (26%)
KELCH repeat 432..475 CDD:276965 12/45 (27%)
KELCH repeat 479..523 CDD:276965 14/43 (33%)
Kelch 490..536 CDD:128874 15/45 (33%)
Kelch_1 525..570 CDD:279660 9/44 (20%)
KELCH repeat 526..571 CDD:276965 9/44 (20%)
Kelch_1 573..617 CDD:279660 11/58 (19%)
KELCH repeat 573..617 CDD:276965 11/58 (19%)
Kbtbd13NP_083250.1 BTB 13..100 CDD:197585
Kelch 1 159..209 6/27 (22%)
Kelch_1 202..244 CDD:279660 12/42 (29%)
KELCH repeat 202..244 CDD:276965 12/42 (29%)
Kelch 2 210..258 12/48 (25%)
Kelch_1 247..292 CDD:279660 14/44 (32%)
KELCH repeat 248..292 CDD:276965 14/43 (33%)
Kelch 3 259..305 15/45 (33%)
KELCH repeat 295..336 CDD:276965 8/42 (19%)
Kelch 4 307..350 8/45 (18%)
KELCH repeat 338..383 CDD:276965 11/47 (23%)
Kelch 5 352..400 9/49 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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