Protein Alignment klhl10 and klhl13

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: XP_031746247.1
• Gene: klhl13 / 493457
• XenbaseID: XB-GENE-923144
• Length: 655
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 158/613 - (25%)
• Similarity: 278/613 - (45%)
• Gaps: 57/613 - (9%)

  Fly    26 VSMDSLQLNADGNSPEDKTLGIGRKTILNAHTKSLAPIVSDEALNTLNELREQNLLCDAQI--SV 88
            ||:.:..:....:....|| |..|....|.|        |...|...::||.:.||||..:  ..
 Frog    45 VSLGNNDMGVSAHLQSSKT-GTTRFFTSNTH--------SSVVLQGFDQLRIEGLLCDVTLVPGD 100

  Fly    89 GEDVFNVHRAIMCSCSSYFRAQFTGFNADTPGCVDGSDAKKNNNF--IHIPGVSSCIMNCVIQYA 151
            |:::|.||||:|.|.|.||:|.|||             ..|..:.  |.:.||:...:..:|.:.
 Frog   101 GDEIFPVHRAMMASSSDYFKAMFTG-------------GMKEQDLMCIKLHGVNKIGLKKIIDFI 152

  Fly   152 YLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRILTPENCVSIMGFARFRFLEDLHLKARN 216
            |..:.:::..|:.:.|..|.::.::.::..||.:|...:|.||||.:...|....|.::.....|
 Frog   153 YTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVTLENCVEVGRIANTYNLTEVDKYVNN 217

  Fly   217 YTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTREEDHVWKLCVKWIDRNPESRKRHVAHLMT 281
            |.|:.|..:.... :.:.:..:....::|.:.|....|..::|...:|: |..::|..:.|.:|.
 Frog   218 YILKNFPALLTTG-EFVKLPFDRLAFVLSSNSLKQCTELELFKAACRWL-RYEDARMEYAAKIMK 280

  Fly   282 GVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLDFLNP--QADELTTPPLAMPRLP 344
            .:|..||||:..:..|:...::........|:::...:.. :.::.|  |::....      |..
 Frog   281 NIRFPLMTPQDLINHVQTVDFMRTDNTCVNLLLEASNYQM-MPYMQPVMQSERTAI------RSD 338

  Fly   345 HEVIFAIGG---WSGGTSKGCIETYDTRADRWVTINAEDPAGPRAYHGTAVLGFKIFSIGG---Y 403
            :..:..:||   .....||. :..||.:...|.::...|  .||..||.||:|..::.:||   |
 Frog   339 NTHLVTLGGVLRQQLVVSKE-LRMYDEKGHEWKSLAPMD--APRYQHGIAVIGNFLYVVGGQSNY 400

  Fly   404 D--GVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYDGHNRLNTVERYNPRT 466
            |  |....:|...||....||.::|.::.:|.:..::.|.|.:||:||.:....|.|||.|||||
 Frog   401 DTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRNAAGELATVECYNPRT 465

  Fly   467 NQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSC 531
            |:||.:..||......:.......:|.:||............:||.|:.||:...|...| |:.|
 Frog   466 NEWSYVAKMNEPHYGHAGTVFGGLMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVR-GLHC 529

  Fly   532 V-AFRNQLYVIGG--FNGTA---RLSTGERFDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGG 590
            : ...::||||||  |.||:   .:.:.|.:.|....|..|..|...:|:.|:.:.::.|:.:||
 Frog   530 MCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSPSLDQWTPIAAMLRGQSDVGVAVFENKIYVVGG 594

  Fly   591 F--NGVSTISHTECYVAETDEWMEATDM 616
            :  |....:...:.|..|.|||.:..|:
 Frog   595 YSWNNRCMVEIVQKYDPEKDEWHKVFDL 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	18/47 (38%)
		PHA03098	86..610	CDD:222983	139/545 (26%)
		KELCH repeat	385..428	CDD:276965	17/47 (36%)
		KELCH repeat	432..475	CDD:276965	19/42 (45%)
		KELCH repeat	479..523	CDD:276965	8/43 (19%)
		KELCH repeat	526..571	CDD:276965	17/50 (34%)
		KELCH repeat	573..617	CDD:276965	12/46 (26%)
klhl13	XP_031746247.1	BTB_POZ_KLHL9_13	69..196	CDD:349548	39/147 (27%)
		PHA03098	92..635	CDD:222983	144/557 (26%)
		KELCH repeat	379..427	CDD:276965	17/47 (36%)
		KELCH repeat	431..475	CDD:276965	19/43 (44%)
		KELCH repeat	478..523	CDD:276965	9/44 (20%)
		KELCH repeat	525..574	CDD:276965	16/49 (33%)
		KELCH repeat	577..624	CDD:276965	12/46 (26%)