Protein Alignment klhl10 and klhl20

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_998166.2
• Gene: klhl20 / 406274
• ZFINID: ZDB-GENE-040426-1935
• Length: 591
• Species: Danio rerio
• Alignment Length: 614
• Identity: 190/614 - (30%)
• Similarity: 274/614 - (44%)
• Gaps: 84/614 - (13%)

  Fly    44 TLGIGRKTILNAHTKSLAPIVSD----EALNTLNELREQNLLCDAQISVGEDVFNVHRAIMCSCS 104
            |||...|........:..|.:||    :.|..:|.||:...|||..:.||......||.|:.:||
Zfish     8 TLGDPNKLPEGVPQPARMPYISDKHPRQTLEVINLLRKHRELCDVVLVVGAKKIYAHRVILSACS 72

  Fly   105 SYFRAQFTGFNADTPGCVDGSDAKKNNNFIHIPGVSSCIMNCVIQYAYLRQTNISESNVHELLIC 169
            .||||.||           |..|:.....:.|..:....|..:|.:||..|..:.|.||..||..
Zfish    73 PYFRAMFT-----------GELAESRQTEVVIRDIDERAMELLIDFAYTSQVTVEEGNVQTLLPA 126

  Fly   170 ADYVGMVGLVKKCKDYLGRILTPENCVSIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILD 234
            |..:.:..:.:.|.::|.|.|.|.||:.|..||......:|...|..:|...|.|| ..:.:.:.
Zfish   127 ACLLQLAEIQEACCEFLKRQLDPSNCLGIRAFADTHSCRELLRIADKFTQHNFQEV-MESEEFML 190

  Fly   235 MSAEDFYSIISDDELNTREEDHVWKLCVKWIDRNPESRKRHVAHLMTGVRLGLMTPKCFMEEVKE 299
            :.|.....|||.||||.|.|:.|:...:.|:..:.:.|:..:..::..|||.|::||..:..|..
Zfish   191 LPANQLIDIISSDELNVRSEEQVFNAVMAWVKYSIQERRPQLPQVLQHVRLPLLSPKFLVGTVGS 255

  Fly   300 HPYVLECEAAKPLIVDTFKFMYDLDFLNPQADELTTPPLAMPRLP---HEVIFAIGGWSGGTSKG 361
            .|.:...|..:.|:.:...::     |.||...|...|...||.|   .||:||:|||..|.:..
Zfish   256 DPLIKSDEECRDLVDEAKNYL-----LLPQERPLMQGPRTRPRKPIRCGEVLFAVGGWCSGDAIS 315

  Fly   362 CIETYDTRADRW----------------------------------VTINAEDP--------AGP 384
            .:|.||.:.:.|                                  .::...||        ..|
Zfish   316 SVERYDPQTNEWRMVASMSKRRCGVGVSVLDDLLYAVGGHDGSSYLNSVERYDPKTNQWSSDVAP 380

  Fly   385 ----RAYHGTAVLGFKIFSIGGYDGVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIY 445
                |...|.||||..::::||.|||...|....:|..:.||..:|.|..||..|:|..|.|.:|
Zfish   381 TSTCRTSVGVAVLGGYLYAVGGQDGVSCLNIVERYDPKENKWTRVASMSTRRLGVAVAVLGGFLY 445

  Fly   446 AIGGYDGHNRLNTVERYNPRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYD 510
            |:||.||.:.|||||||||:.|:|..:.||..:|........|:.||:.||.:....|.|||.|:
Zfish   446 AVGGSDGTSPLNTVERYNPQENRWHTVAPMGTRRKHLGCAVYQDMIYSVGGRDDTTELSSAERYN 510

  Fly   511 PVTNVWTRIPNMNHRRSGVSCVAFRNQLYVIGGFNGTARLSTGERFDPDTQTWHFIREMNHSRSN 575
            |.||.|:.:..|..|||||.......||..:|||:||..|.|.|.:|||..||.....||:.|
Zfish   511 PRTNQWSPVVAMTSRRSGVGLAVVNGQLMAVGGFDGTTYLKTIEVYDPDANTWRLYGGMNYRR-- 573

  Fly   576 FGLEIIDDMIFAIGGFNGVSTISHTECYV 604
                        :||..||..::|.|.::
Zfish   574 ------------LGGGVGVIKMTHCESHI 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	18/49 (37%)
		PHA03098	86..610	CDD:222983	176/568 (31%)
		KELCH repeat	385..428	CDD:276965	16/42 (38%)
		KELCH repeat	432..475	CDD:276965	22/42 (52%)
		KELCH repeat	479..523	CDD:276965	15/43 (35%)
		KELCH repeat	526..571	CDD:276965	20/44 (45%)
		KELCH repeat	573..617	CDD:276965	7/32 (22%)
klhl20	NP_998166.2	None