Protein Alignment klhl10 and ivns1abpa

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_954973.2
• Gene: ivns1abpa / 387591
• ZFINID: ZDB-GENE-031222-2
• Length: 643
• Species: Danio rerio
• Alignment Length: 655
• Identity: 155/655 - (23%)
• Similarity: 255/655 - (38%)
• Gaps: 137/655 - (20%)

  Fly    66 DEALNTLNELREQNLLCDAQISVGEDVFNVHRAIMCSCSSYFRAQFTGFNADTPGCVDGSDAKKN 130
            |..:..:|.||:....||.::.|.......|||::..||.|.   |..||:|.          :.
Zfish    16 DSTVAKMNALRKNGQFCDVRLQVCGHELMAHRAVLACCSPYL---FEIFNSDL----------EP 67

  Fly   131 NNFIHI------PGVSSCIMNCVIQYAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRI 189
            :...|:      |.....::|    |||..|....:..|.|:...|..:.|..:.:.|.|||...
Zfish    68 HGISHVKFEDLDPEAVEILLN----YAYTAQLKADKELVKEVYSAAKRLKMDRVKQICGDYLLSK 128

  Fly   190 LTPENCVSIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILDMSAEDF-------YSIISDD 247
            :..::.:|...||.......|..|..:|...:..||:         ..|||       ..::.:|
Zfish   129 MDSQSAISYRNFASCMGDGRLLGKIDSYIQEHLLEVS---------EQEDFLKLPRLKLEVMLED 184

  Fly   248 ELNTREEDHVWKLCVKWIDR----NPESRKRHVAHLMT-----------GVRL------------ 285
            .|.......::...:.|:.|    |.|..:|.:..:.|           |..|
Zfish   185 NLTLPSNGKLYSKVIGWVQRSLWENGEPLERLMEEVQTLYYSADHKLLDGSLLDGQAEVFGTEDD 249

  Fly   286 -----------------------GLMTPKCFMEEVK-EHPYVLECEAAKPLIVDTFKFMYDLD-- 324
                                   |.::|.......| |..|:    |::....:|:..:..|:
Zfish   250 HIQFVQKKPPRENVHRQLSTSSSGSLSPGSTKHPCKQEWKYI----ASEKTTNNTYLCLAVLNGM 310

  Fly   325 ----FL----NPQADELTTP----------------------PLAMPRLP------HEVIFAIGG 353
                ||    :|||....||                      |:...|..      ::.:.|.||
Zfish   311 LCVIFLHGRSSPQASPSATPCLTKSLSFEGQPLEEEPDKLLSPMHYARSGLGIASLNDQLIAAGG 375

  Fly   354 WSGGTSKGCIETYDTRADRWVTINAEDPAGPRAYHGTAVLGFKIFSIGGYDGVEYFNTC-RVFDA 417
            ::.......:|.|:.:.:.|..|  .....|||....|||..:::.:||.:|.....:| ..::.
Zfish   376 YNREECLRTVECYNIKTNSWTFI--APMRTPRARFQMAVLMGQLYVMGGSNGHSDELSCGETYNP 438

  Fly   418 VKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYD--GHNRLNTVERYNPRTNQWSVIPPMNMQRS 480
            ...:|.::..:...||...|..||..:|.:||.|  |...|...:.::|.:..|:...|:|::|.
Zfish   439 NADEWTQVPELRTNRCNAGVCSLNNKLYVVGGSDPCGQKGLKNCDVFDPISKAWTNCAPLNIRRH 503

  Fly   481 DASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQLYVIGGFN 545
            .|:.|.|...:|..||.....||:|.|.|:|..|.||.|.:||..|.|.....:..:|:|:|||:
Zfish   504 QAAVCELDGFMYVIGGAESWNCLNSVERYNPENNTWTLIASMNIARRGAGVAVYEGKLFVVGGFD 568

  Fly   546 GTARLSTGERFDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTISHTECYVAETDEW 610
            |:..|...|.:||....|..:..||..|||.|..:::|:|:|||||:|...::..|.|..:|:||
Zfish   569 GSHALRCVEMYDPVRNEWRMLGSMNSPRSNAGAAVLNDVIYAIGGFDGNDFLNSVEAYNPKTEEW 633

  Fly   611 MEATD 615
            ....|
Zfish   634 STCAD 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	13/41 (32%)
		PHA03098	86..610	CDD:222983	146/628 (23%)
		KELCH repeat	385..428	CDD:276965	10/43 (23%)
		KELCH repeat	432..475	CDD:276965	13/44 (30%)
		KELCH repeat	479..523	CDD:276965	17/43 (40%)
		KELCH repeat	526..571	CDD:276965	14/44 (32%)
		KELCH repeat	573..617	CDD:276965	18/43 (42%)
ivns1abpa	NP_954973.2	BTB_POZ_NS1BP	14..137	CDD:349615	32/137 (23%)
		BACK_NS1BP_IVNS1ABP	129..225	CDD:350577	19/104 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..282		2/24 (8%)
		NanM	351..613	CDD:442289	77/263 (29%)
		KELCH repeat	358..401	CDD:276965	8/44 (18%)
		Kelch 1	369..415		13/47 (28%)
		KELCH repeat	405..450	CDD:276965	10/44 (23%)
		Kelch 2	416..463		9/46 (20%)
		KELCH repeat	453..498	CDD:276965	13/44 (30%)
		Kelch 3	465..512		14/46 (30%)
		KELCH repeat	502..545	CDD:276965	17/42 (40%)
		Kelch 4	513..559		17/45 (38%)
		KELCH repeat	549..593	CDD:276965	13/43 (30%)
		Kelch 5	560..606		17/45 (38%)
		Kelch_1	595..638	CDD:396078	17/42 (40%)
		KELCH repeat	596..638	CDD:276965	17/41 (41%)
		Kelch 6	608..643		13/31 (42%)