Protein Alignment klhl10 and ivns1abpb

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_958891.1
• Gene: ivns1abpb / 334334
• ZFINID: ZDB-GENE-030131-6266
• Length: 640
• Species: Danio rerio
• Alignment Length: 652
• Identity: 152/652 - (23%)
• Similarity: 269/652 - (41%)
• Gaps: 127/652 - (19%)

  Fly    66 DEALNTLNELREQNLLCDAQISVGEDVFNVHRAIMCSCSSYFRAQFTGFNADTPGCVDGSDAKKN 130
            |..:..:|.||:....||.::.|.......|:|::..||.|.   |..|||||       :.:..
Zfish    16 DSTVAKMNALRKSGQFCDVRLLVCGHELMAHKAVLACCSPYL---FEIFNADT-------EPQGG 70

  Fly   131 NNFIHIPGVSSCIMNCVIQYAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRILTPENC 195
            .:.:....::...|..::.|||..|....:|.|.::...|..:.:..:.:.|.:||...:..::.
Zfish    71 VSLVKFDDLNPDAMEVLLNYAYTAQLKADKSLVSDVYSAAKKLKLERVKQICGEYLLSKMDSQSA 135

  Fly   196 VSIMGFA---------------------------------RFR---FLED-LHL----KARNYTL 219
            :|...||                                 |.:   .||| |:|    |..:..:
Zfish   136 ISYRNFASSMADGRLLGKIDGYIQDHLHEISEQDDFLKLPRLKLEVMLEDNLNLPGNGKLYSKVI 200

  Fly   220 RYFTEVAYRNIDILDMSAED----FYSIISDDELN------------TREEDHVWKLCVKWIDRN 268
            .:.....::|.|.|:...|:    :||  :|.:|:            :.|:||     ::::.:.
Zfish   201 SWVQRSLWKNGDPLEKLMEEVQTLYYS--ADHKLHDGSLLEGQAEVCSTEDDH-----IQFVQKK 258

  Fly   269 PESRK-----------------------RHVA--------HLMTGVRLGLMTPKCFMEEVKEHPY 302
            |...:                       :::|        :|...|..||:...........|
Zfish   259 PPRERDEMGSGASGSISPSNSQFNKHEWKYIASEKTTSNSYLCLAVLRGLLCVISLHGRTSPH-- 321

  Fly   303 VLECEAAKPLIVDTFKFMYDLDFLNPQADELTTP------PLAMPRLPHEVIFAIGGWSGGTSKG 361
              ...:|.|.::.:..|...|:.|.   ::|..|      .|....|..::| |.||::......
Zfish   322 --NSPSATPCVLKSPNFEAQLEDLQ---EKLLKPMHYARSGLGTAELDCKLI-AAGGYNREECLR 380

  Fly   362 CIETYDTRADRWVTINAEDPAGPRAYHGTAVLGFKIFSIGGYDGVEYFNTC-RVFDAVKKKWNEI 425
            .:|.||.:.|.|..|  .....|||....|||..:::.:||.:|.....:| .:::....:|.::
Zfish   381 TVECYDPKKDCWTFI--APMRTPRARFQMAVLMGEVYVMGGSNGHSDELSCGEMYNPRADEWIQV 443

  Fly   426 APMHCRRCYVSVTELNGMIYAIGGYD--GHNRLNTVERYNPRTNQWSVIPPMNMQRSDASACTLQ 488
            ..:...||...|..|...::.:||.|  |...|...:.::|.|..|:...|:|::|..|:.|.|.
Zfish   444 PELRTNRCNAGVCSLQNKLFVVGGSDPCGQKGLKNCDSFDPVTKMWTSCAPLNIKRHQAAVCELS 508

  Fly   489 ERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQLYVIGGFNGTARLSTG 553
            ..:|..||.....||:|.|.|:|..|.||.:.:||..|.|.....:..:|:|:|||:|:..|...
Zfish   509 GYMYVIGGAESWNCLNSVERYNPENNTWTLVASMNVARRGAGVAVYEGKLFVVGGFDGSHALRCV 573

  Fly   554 ERFDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTISHTECYVAETDEW---MEATD 615
            |.:||.|..|..:..|..:|||.||.::::::.|:|||:|...::..|.|..|.:||   :||..
Zfish   574 EVYDPATNEWRMLGSMTSARSNAGLAVLNNVLCAVGGFDGNEFLNSMEVYNLEKNEWSPFIEALG 638

  Fly   616 MN 617
            .|
Zfish   639 KN 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	12/41 (29%)
		PHA03098	86..610	CDD:222983	141/620 (23%)
		KELCH repeat	385..428	CDD:276965	10/43 (23%)
		KELCH repeat	432..475	CDD:276965	12/44 (27%)
		KELCH repeat	479..523	CDD:276965	16/43 (37%)
		KELCH repeat	526..571	CDD:276965	15/44 (34%)
		KELCH repeat	573..617	CDD:276965	17/46 (37%)
ivns1abpb	NP_958891.1	BTB_POZ_NS1BP	14..138	CDD:349615	29/131 (22%)
		BACK_NS1BP_IVNS1ABP	130..226	CDD:350577	14/95 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..278		1/20 (5%)
		NanM	348..624	CDD:442289	82/278 (29%)
		KELCH repeat	355..399	CDD:276965	12/46 (26%)
		Kelch 1	366..412		16/48 (33%)
		KELCH repeat	402..446	CDD:276965	10/43 (23%)
		Kelch 2	413..460		9/46 (20%)
		KELCH repeat	450..495	CDD:276965	12/44 (27%)
		Kelch 3	462..509		14/46 (30%)
		KELCH repeat	499..542	CDD:276965	16/42 (38%)
		Kelch 4	510..556		16/45 (36%)
		KELCH repeat	546..590	CDD:276965	14/43 (33%)
		Kelch 5	557..603		18/45 (40%)
		KELCH repeat	593..632	CDD:276965	15/38 (39%)
		Kelch 6	605..640		12/34 (35%)